Two New Isoquinoline Alkaloids from the Barks of Cassia fistula and Their Anti-Tobacco Mosaic Virus Activity

被引：10
作者：
Zhou, Ling [1 ,2 ,3 ]
Liu, Li-Xuang [3 ]
Yang, Guo-Rong [3 ]
Xing, Huan-Huan [1 ,2 ]
Ma, Hang-Ying [1 ,2 ]
Yang, Yan [1 ,2 ]
Wang, Ye-De [1 ,2 ]
Zhou, Kun [1 ,2 ]
Wei-Dong [1 ,2 ]
Zhou, Min [1 ,2 ]
Ye, Yan-Qing [1 ,2 ]
Hu, Qiu-Fen [1 ,2 ]
机构：
[1] Yunnan Minzu Univ, Key Lab Chem Ethn Med Resources, State Ethn Affairs Commiss, Kunming 650031, Peoples R China
[2] Yunnan Minzu Univ, Minist Educ, Kunming 650031, Peoples R China
[3] China Tobacco Yunnan Ind Co Ltd, Key Lab Tobacco Chem Yunnan Prov, Kunming 650231, Peoples R China
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2017年 / 53卷 / 03期
基金：
中国国家自然科学基金;
关键词：
isoquinoline alkaloids; Cassia fistula; anti-tobacco mosaic virus activity; STEMS; DERIVATIVES; CHROMONES;
D O I：
10.1007/s10600-017-2033-0
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Two new isoquinoline alkaloids, fistulaquinolines A and B (1 and 2), were isolated from the barks of Cassia fistula. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1 and 2 were tested for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that the two compounds showed weak anti-TMV activity with inhibition rates of 18.9 and 22.6%.
引用
收藏
页码：508 / 511
页数：4
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