Two New Isoquinoline Alkaloids from the Barks of Cassia fistula and Their Anti-Tobacco Mosaic Virus Activity

被引：10

作者：

Zhou, Ling ^{[1
,2
,3
]}

Liu, Li-Xuang ^{[3
]}

Yang, Guo-Rong ^{[3
]}

Xing, Huan-Huan ^{[1
,2
]}

Ma, Hang-Ying ^{[1
,2
]}

Yang, Yan ^{[1
,2
]}

Wang, Ye-De ^{[1
,2
]}

Zhou, Kun ^{[1
,2
]}

Wei-Dong ^{[1
,2
]}

Zhou, Min ^{[1
,2
]}

Ye, Yan-Qing ^{[1
,2
]}

Hu, Qiu-Fen ^{[1
,2
]}

机构：

[1] Yunnan Minzu Univ, Key Lab Chem Ethn Med Resources, State Ethn Affairs Commiss, Kunming 650031, Peoples R China

[2] Yunnan Minzu Univ, Minist Educ, Kunming 650031, Peoples R China

[3] China Tobacco Yunnan Ind Co Ltd, Key Lab Tobacco Chem Yunnan Prov, Kunming 650231, Peoples R China

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2017年 / 53卷 / 03期

基金：

中国国家自然科学基金;

关键词：

isoquinoline alkaloids; Cassia fistula; anti-tobacco mosaic virus activity; STEMS; DERIVATIVES; CHROMONES;

D O I：

10.1007/s10600-017-2033-0

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two new isoquinoline alkaloids, fistulaquinolines A and B (1 and 2), were isolated from the barks of Cassia fistula. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1 and 2 were tested for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that the two compounds showed weak anti-TMV activity with inhibition rates of 18.9 and 22.6%.

引用

页码：508 / 511

页数：4

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