Subcellular detection and localization of the drug transporter P-glycoprotein in cultured tumor cells

被引:71
作者
Molinari, A
Calcabrini, A
Meschini, S
Stringaro, A
Crateri, P
Toccacieli, L
Marra, M
Colone, M
Cianfriglia, M
Arancia, G
机构
[1] Ist Super Sanita, Ultrastrutture Lab, I-00161 Rome, Italy
[2] Ist Super Sanita, Immunol Lab, I-00161 Rome, Italy
关键词
D O I
10.2174/1389203023380413
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In vitro studies on the cellular location of P-glycoprotein (Pgp) are reported with the aim to clarify the relationship between its intracellular expression and the multidrug resistance (MDR) level of tumor cells.
引用
收藏
页码:653 / 670
页数:18
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