Clinical Consensus Recommendations for Urine Testing of Adherence to Antipsychotics Among People With Serious Mental Illness

被引：6

作者：

Cohen, Amy N. ^{[1
]}

Collins, Gretchen ^{[2
,3
]}

Nucifora, Frederick Charles, Jr. ^{[4
]}

Strobel, Roddy ^{[5
]}

Wait, David B. ^{[6
]}

Young, Alexander S. ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Dept Psychiat & Biobehav Sci, Los Angeles, CA 90024 USA

[2] View Point Hlth, Lawrenceville, GA USA

[3] Emory Univ, Dept Psychiat, Atlanta, GA 30322 USA

[4] Johns Hopkins Univ, Dept Psychiat & Behav Sci, Baltimore, MD USA

[5] Permian Basin Community Ctr, Midland, TX USA

[6] Heritage Hlth, Coeur Dalene, ID USA

来源：

PSYCHIATRIC SERVICES | 2018年 / 69卷 / 03期

关键词：

MEDICATION ADHERENCE; SCHIZOPHRENIA;

D O I：

10.1176/appi.ps.201700082

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

Objective: This study developed clinical recommendations for the use of proven urine testing technologies to assess antipsychotic medication adherence among people with serious mental illness. Methods: Guided by the RAND/UCLA Appropriateness Method, researchers conducted a literature review and semistructured interviews and convened an expert panel to develop clinical consensus recommendations for the use of urine monitoring to assess antipsychotic medication adherence. Results: The expert panel identified six circumstances in which urine monitoring was recommended at initial evaluation and five scenarios in which monitoring was recommended after initial evaluation. Conducting monitoring at the site where psychiatric medication is prescribed and providing education prior to testing and feedback after testing were recommended. Conclusions: A consensus was reached on clinical recommendations for use of urine monitoring at intake and during ongoing treatment. There was strong agreement that monitoring can be used to improve assessment and thence clinical care and outcomes.

引用

页码：345 / 348

页数：4

共 11 条

[1] Medication adherence and long-term functional outcomes in the treatment of schizophrenia in usual care [J].

Ascher-Svanum, H ;

Faries, DE ;

Zhu, BJ ;

Ernst, FR ;

Swartz, MS ;

Swanson, JW .

JOURNAL OF CLINICAL PSYCHIATRY, 2006, 67 (03) :453-460

[2] The 2009 Schizophrenia PORT Psychopharmacological Treatment Recommendations and Summary Statements [J].

Buchanan, Robert W. ;

Kreyenbuhl, Julie ;

Kelly, Deanna L. ;

Noel, Jason M. ;

Boggs, Douglas L. ;

Fischer, Bernard A. ;

Himelhoch, Seth ;

Fang, Beverly ;

Peterson, Eunice ;

Aquino, Patrick R. ;

Keller, William .

SCHIZOPHRENIA BULLETIN, 2010, 36 (01) :71-93

[3] Antipsychotic medication adherence: Is there a difference between typical and atypical agents? [J].

Dolder, CR ;

Lacro, JP ;

Dunn, LB ;

Jeste, DV .

AMERICAN JOURNAL OF PSYCHIATRY, 2002, 159 (01) :103-108

[4]

Dretchen KL, 2013, J PHARM CLIN TOXICOL, V1, P1014

[5]

Fitch KBSJ., 2001, The RAND/UCLA appropriateness method user's manual. RAND

[6] Adherence to treatment with antipsychotic medication and health care costs among medicaid beneficiaries with schizophrenia [J].

Gilmer, TP ;

Dolder, CR ;

Lacro, JP ;

Folsom, DP ;

Lindamer, L ;

Garcia, P ;

Jeste, DV .

AMERICAN JOURNAL OF PSYCHIATRY, 2004, 161 (04) :692-699

[7] Quantitative levels of aripiprazole parent drug and metabolites in urine [J].

McEvoy, Joseph ;

Millet, Robert A. ;

Dretchen, Kenneth ;

Morris, Ayodele A. ;

Corwin, Michael J. ;

Buckley, Peter .

PSYCHOPHARMACOLOGY, 2014, 231 (23) :4421-4428

[8] Improving Antipsychotic Adherence Among Patients With Schizophrenia: Savings for States [J].

Predmore, Zachary S. ;

Mattke, Soeren ;

Horvitz-Lennon, Marcela .

PSYCHIATRIC SERVICES, 2015, 66 (04) :343-345

[9] Relationships among subjective and objective measures of adherence to oral antipsychotic medications [J].

Velligan, Dawn I. ;

Wang, Mei ;

Diamond, Pamela ;

Glahn, David C. ;

Castillo, Desiree ;

Bendle, Scott ;

Lam, Y. W. Francis ;

Ereshefsky, Larry ;

Miller, Alexander L. .

PSYCHIATRIC SERVICES, 2007, 58 (09) :1187-1192

[10] Defining and assessing adherence to oral antipsychotics: A review of the literature [J].

Velligan, Dawn I. ;

Lam, Yui-Wing Francis ;

Glahn, David C. ;

Barrett, Jennifer A. ;

Maples, Natalie J. ;

Ereshefsky, Larry ;

Miller, Alexander L. .

SCHIZOPHRENIA BULLETIN, 2006, 32 (04) :724-742

← 1 2 →