Management of cutaneous T-cell lymphomas: Established and emergent therapies

被引:1
作者
Wain, Thevaki [1 ]
Venning, Victoria L. [2 ,3 ]
Consuegra, Germana [1 ,3 ]
Fernandez-Penas, Pablo [1 ,2 ,3 ]
Wells, Jillian [1 ,3 ]
机构
[1] Westmead Hosp, Dept Dermatol, Westmead, NSW, Australia
[2] Skin Hosp, 7 Ashley Lane, Westmead, NSW, Australia
[3] Univ Sydney, Fac Med, Sydney, NSW, Australia
关键词
cutaneous lymphoproliferative disorders; cutaneous T-cell lymphoma; management; mycosis fungoides; Sezary syndrome; ELECTRON-BEAM THERAPY; ADVANCED MYCOSIS-FUNGOIDES; LOW-DOSE METHOTREXATE; MULTICENTER PHASE-II; SEZARY-SYNDROME; CLINICAL-TRIAL; STAGE; CHEMOTHERAPY; DISEASE; INTERFERON;
D O I
10.1111/ajd.13011
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Cutaneous T-cell lymphoma is an uncommon group of non-Hodgkin's lymphoma primarily affecting the skin. It is comprised of a variety of entities with different clinical behaviours and prognosis. Mycosis fungoides is the commonest subtype, and Sezary syndrome is a much rarer form of cutaneous T-cell lymphoma. At this stage, control rather than cure is the goal of therapy, with particular emphasis placed on preserving quality of life. Our review of the efficacy, safety profile and accessibility of treatment modalities for mycosis fungoides/Sezary syndrome is a tailored guide for the clinician treating these rare conditions.
引用
收藏
页码:200 / 208
页数:9
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