Spanish Multidisciplinary Melanoma Group (GEM) guidelines for the management of patients with advanced melanoma

被引：7

作者：

Berrocal, Alfonso ^{[1
]}

Espinosa, Enrique ^{[2
]}

Marin, Severiano ^{[3
]}

Malvehy, Josep ^{[4
]}

Moreno, David ^{[5
]}

Dolores Lozano, Maria ^{[6
]}

Martin-Algarra, Salvador ^{[7
]}

Antonio Lopez, Jose ^{[8
]}

Conill, Carlos ^{[9
]}

Luis Rodriguez-Peralto, Jose ^{[10
]}

机构：

[1] Hosp La Paz, Dept Oncol, Madrid, Spain

[2] Hosp La Paz, Serv Oncol, Madrid, Spain

[3] Consorcio Hosp Gen Univ, Plast Surg, Valencia 46014, Spain

[4] Hosp Clin Barcelona, Melanoma Unit, Dept Dermatol, Barcelona, Spain

[5] Hosp Univ Virgen Macarena, Dermatol Unit, Seville, Spain

[6] Univ Navarra Clin, Dept Pathol, Pamplona, Spain

[7] Univ Navarra Clin, Dept Oncol, Pamplona, Spain

[8] Univ Barcelona, Inst Invest Biomed August Pi & Sunyer IDIBAPS, Hosp Clin, Dept Oncol, E-08007 Barcelona, Spain

[9] Univ Barcelona, Inst Invest Biomed August Pi & Sunyer IDIBAPS, Hosp Clin, Dept Radiat Oncol, E-08007 Barcelona, Spain

[10] Hosp 12 Octubre, Dept Pathol, E-28041 Madrid, Spain

来源：

EUROPEAN JOURNAL OF DERMATOLOGY | 2015年 / 25卷 / 05期

关键词：

advanced melanoma; diagnosis; therapeutic management; CUTANEOUS MALIGNANT-MELANOMA; HIGH-RISK MELANOMA; STAGE-IV MELANOMA; UNDERGO COMPLETION LYMPHADENECTOMY; CLINICAL-PRACTICE GUIDELINES; REGIONAL NODAL METASTASES; RANDOMIZED SURGICAL TRIAL; SENTINEL LYMPH-NODE; PHASE-III TRIAL; FOLLOW-UP;

D O I：

10.1684/ejd.2015.2594

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Advanced melanoma is a relatively uncommon condition whose therapeutic management has undergone major changes over the past four years. The present article aims to establish recommendations for the management of these patients based on the best available evidence reached by consensus of a group of professionals familiar in the treatment of these patients. These professionals, belonging to Spanish Multidisciplinary Melanoma Group, reviewed the diagnostic process and the incorporation of new techniques of molecular diagnosis of advanced disease; treatment and monitoring of stage III both as adjuvant locoregional treatments have been addressed, as well as new therapies for stage IV. We have reviewed the palliative treatment alternatives for disseminated disease, such as surgery, radiotherapy or non-cytotoxic systemic treatments. Finally, we have also reviewed the most relevant toxicities of new drugs and their management in clinical practice.

引用

页码：392 / 403

页数：12

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