Auditory temporal processing deficits in patients with insular stroke

被引:88
作者
Bamiou, D. -E.
Musiek, F. E.
Stow, I.
Stevens, J.
Cipolotti, L.
Brown, M. M.
Luxon, L. M.
机构
[1] Natl Hosp Neurol & Neurosurg, Dept Neurootol, London WC1N 3BG, England
[2] Natl Hosp Neurol & Neurosurg, Neuropsychol Dept, London WC1N 3BG, England
[3] Natl Hosp Neurol & Neurosurg, Dept Radiol, London WC1N 3BG, England
[4] Inst Child Hlth, Acad Unit Audiol Med, London, England
[5] UCL, Inst Neurol, Stroke Res Grp, London WC1E 6BT, England
[6] UCL, Audiol Med, Inst Child Hlth, London, England
[7] Univ London, London WC1E 7HU, England
[8] Univ Connecticut, DCP Comm Ctr, Storrs, CT USA
关键词
D O I
10.1212/01.wnl.0000230197.40410.db
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objective: To assess central auditory function in a series of patients with stroke of the insula and adjacent areas. Methods: The authors recruited eight patients with stroke affecting the insula and adjacent areas and eight neurologically normal controls (matched to the patients for age, sex, handedness, and hearing thresholds). The lesion spared the adjacent auditory areas in three patients and included other auditory structures in five cases. The authors conducted pure-tone audiometry and tympanometry and a central auditory test battery, which included the dichotic digits, and three temporal tests, the duration pattern, frequency pattern, and gaps in noise tests. They collected information from the hospital notes on symptoms at presentation and neuropsychological assessment data during the acute phase. Results: The central auditory tests gave normal results in all controls. The temporal tests gave abnormal results in all three cases in which other auditory areas were spared, as well as in the other five cases. Results of the gaps in noise test were abnormal contralaterally to the lesion in three and bilaterally in five cases. The central auditory deficits did not cosegregate with the presence of cognitive impairment during the acute stage. Conclusion: Insular lesions may affect central auditory function and, in particular, temporal resolution and sequencing, consistent with neuroimaging studies.
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收藏
页码:614 / 619
页数:6
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