Headache and changes in artwork as a presentation of central venous sinus thrombosis in a child with acute lymphoblastic leukemia

被引：0

作者：

Manoukian, Martin A. C. ^{[1
]}

Panigrahi, Arun R. ^{[2
]}

Tzimenatos, Leah ^{[1
]}

机构：

[1] Univ Calif Davis, Dept Emergency Med, Sacramento, CA 95817 USA

[2] Univ Calif Davis, Dept Pediat, Div Hematol & Oncol, Sacramento, CA 95817 USA

来源：

AMERICAN JOURNAL OF EMERGENCY MEDICINE | 2022年 / 59卷

关键词：

Acute lymphoblastic leukemia; Induction chemotherapy; Headache; artwork; Central venous sinus thrombosis; Pediatrics; RISK-FACTORS; DIAGNOSIS; THROMBOEMBOLISM; DRAWINGS;

D O I：

10.1016/j.ajem.2022.06.024

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Acute lymphocytic leukemia (ALL) is a common pediatric cancer diagnosis with excellent survival outcomes but significant morbidity, particularly during the induction phase of chemotherapy. Central venous sinus thrombosis (CVST) is a known potential complication of induction therapy; however, it occurs rarely and may be difficult to diagnose, particularly in young children who have limited verbal skills. Herein, we report a case of CVST in a child with B-cell ALL undergoing induction chemotherapy whose main symptoms were headache and a change in the appearance of his artwork noticed by his parents. This astute observation by the child's parents played a critical role in his diagnosis, allowing prompt treatment and eventual recovery. (c) 2022 The Authors. Published by Elsevier Inc.

引用

页码：217.e1 / 217.e3

页数：3

共 18 条

[1] Cerebral venous sinus thrombosis [J].

Capecchi, M. ;

Abbattista, M. ;

Martinelli, I. .

JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2018, 16 (10) :1918-1931

[2] Effect of Endovascular Treatment With Medical Management vs Standard Care on Severe Cerebral Venous Thrombosis The TO-ACT Randomized Clinical Trial [J].

Coutinho, Jonathan M. ;

Zuurbier, Susanna M. ;

Bousser, Marie-Germaine ;

Ji, Xunming ;

Canhao, Patricia ;

Roos, Yvo B. ;

Crassard, Isabelle ;

Nunes, Ana Paiva ;

Uyttenboogaart, Maarten ;

Chen, Jian ;

Emmer, Bart J. ;

Roosendaal, Stefan D. ;

Houdart, Emmanuel ;

Reekers, Jim A. ;

van den Berg, Rene ;

de Haan, Rob J. ;

Majoie, Charles B. ;

Ferro, Jose M. ;

Stam, Jan .

JAMA NEUROLOGY, 2020, 77 (08) :966-973

[3] Headache Diagnosis in Children and Adolescents [J].

Dao, Jasmin M. ;

Qubty, William .

CURRENT PAIN AND HEADACHE REPORTS, 2018, 22 (03)

[4] Cerebral sinovenous thrombosis in children. [J].

deVeber, G ;

Andrew, M ;

Adams, C ;

Bjornson, B ;

Booth, F ;

Buckley, DJ ;

Camfield, CS ;

David, M ;

Humphreys, P ;

Langevin, P ;

MacDonald, EA ;

Gillett, J .

NEW ENGLAND JOURNAL OF MEDICINE, 2001, 345 (06) :417-423

[5] European Stroke Organization guideline for the diagnosis and treatment of cerebral venous thrombosis - endorsed by the European Academy of Neurology [J].

Ferro, J. M. ;

Bousser, M. -G. ;

Canhao, P. ;

Coutinho, J. M. ;

Crassard, I. ;

Dentali, F. ;

di Minno, M. ;

Maino, A. ;

Martinelli, I. ;

Masuhr, F. ;

de Sousa, D. Aguiar ;

Stam, J. .

EUROPEAN JOURNAL OF NEUROLOGY, 2017, 24 (10) :1203-1213

[6] Imaging of cerebral venous thrombosis [J].

Ghoneim, A. ;

Straiton, J. ;

Pollard, C. ;

Macdonald, K. ;

Jampana, R. .

CLINICAL RADIOLOGY, 2020, 75 (04) :254-264

[7] L-asparaginase and venous thromboembolism in acute lymphocytic leukemia [J].

Goyal, Gaurav ;

Bhatt, Vijaya Raj .

FUTURE ONCOLOGY, 2015, 11 (17) :2459-2470

[8] Venous thromboembolism in a large cohort of children with acute lymphoblastic leukemia: Risk factors and effect on prognosis [J].

Klaassen, Irene L. M. ;

Lauw, Mandy N. ;

Fiocco, Marta ;

van der Sluis, Inge M. ;

Pieters, Rob ;

Middeldorp, Saskia ;

van de Wetering, Marianne D. ;

de Groot-Kruseman, Hester A. ;

van Ommen, C. Heleen .

RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS, 2019, 3 (02) :234-241

[9] Rivaroxaban compared with standard anticoagulants for the treatment of acute venous thromboembolism in children: a randomised, controlled, phase 3 trial [J].

Male, Christoph ;

Lensing, Anthonie W. A. ;

Palumbo, Joseph S. ;

Kumar, Riten ;

Nurmeev, Ildar ;

Hege, Kerry ;

Bonnet, Damien ;

Connor, Philip ;

Hooimeijer, Helene L. ;

Torres, Marcela ;

Chan, Anthony K. C. ;

Kenet, Gili ;

Holzhauer, Susanne ;

Santamaria, Amparo ;

Amedro, Pascal ;

Chalmers, Elizabeth ;

Simioni, Paolo ;

Bhat, Rukhmi V. ;

Yee, Donald L. ;

Lvova, Olga ;

Beyer-Westendorf, Jan ;

Biss, Tina T. ;

Martinelli, Ida ;

Saracco, Paola ;

Peters, Marjolein ;

Kallay, Krisztian ;

Gauger, Cynthia A. ;

Massicotte, M. Patricia ;

Young, Guy ;

Pap, Akos F. ;

Majumder, Madhurima ;

Smith, William T. ;

Heubach, Jurgen F. ;

Berkowitz, Scott D. ;

Thelen, Kirstin ;

Kubitza, Dagmar ;

Crowther, Mark ;

Prins, Martin H. ;

Monagle, Paul .

LANCET HAEMATOLOGY, 2020, 7 (01) :E18-E27

[10] Children's Headache: Drawings in the Diagnostic Work Up [J].

Mazzotta, Silvia ;

Pavlidis, Elena ;

Cordori, Cecilia ;

Spagnoli, Carlotta ;

Pini, Luigi Alberto ;

Pisani, Francesco .

NEUROPEDIATRICS, 2015, 46 (04) :261-268

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