Optical coherence tomography (OCT) in neuro-ophthalmology

被引:49
作者
Minakaran, Neda [1 ]
de Carvalho, Emanuel R. [1 ,2 ]
Petzold, Axel [1 ,3 ,4 ]
Wong, Sui H. [1 ,5 ]
机构
[1] Moorfields Eye Hosp NHS Fdn Trust, London, England
[2] Univ Amsterdam, Univ Med Ctr, Dept Ophthalmol, Amsterdam, Netherlands
[3] Univ Amsterdam, Univ Med Ctr, Neuroophthalmol Expertise Ctr, Amsterdam, Netherlands
[4] UCL Inst Neurol, Queen Sq, London, England
[5] Guys & St Thomas NHS Fdn Trust, London, England
关键词
NERVE-FIBER LAYER; GANGLION-CELL COMPLEX; MICROCYSTIC MACULAR EDEMA; VISUAL-FIELD SENSITIVITY; INNER NUCLEAR LAYER; MULTIPLE-SCLEROSIS; BAND ATROPHY; HEAD DRUSEN; NEUROMYELITIS-OPTICA; CHIASMAL COMPRESSION;
D O I
10.1038/s41433-020-01288-x
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Optical coherence tomography (OCT) is a non-invasive medical imaging technology that is playing an increasing role in the routine assessment and management of patients with neuro-ophthalmic conditions. Its ability to characterise the optic nerve head, peripapillary retinal nerve fibre layer and cellular layers of the macula including the ganglion cell layer enables qualitative and quantitative assessment of optic nerve disease. In this review, we discuss technical features of OCT and OCT-based imaging techniques in the neuro-ophthalmic context, potential pitfalls to be aware of, and specific applications in more common neuro-ophthalmic conditions including demyelinating, inflammatory, ischaemic and compressive optic neuropathies, optic disc drusen and raised intracranial pressure. We also review emerging applications of OCT angiography within neuro-ophthalmology.
引用
收藏
页码:17 / 32
页数:16
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