Serum growth arrest-specific protein 6 levels are elevated in adult-onset Still's disease

被引：1

作者：

Kim, Hyoun-Ah ^{[1
]}

Nam, Jin-Young ^{[1
]}

Jung, Ju-Yang ^{[1
]}

Bae, Chang-Bum ^{[1
]}

An, Jeong-Mi ^{[1
]}

Jeon, Ja-Young ^{[1
]}

Kim, Bong-Sik ^{[1
]}

Suh, Chang-Hee ^{[1
,2
]}

机构：

[1] Ajou Univ Sch Med, Dept Rheumatol, Suwon 443721, South Korea

[2] Ajou Univ Sch Med, Div Cell Transformat & Restorat BK21, Suwon 443721, South Korea

来源：

CLINICAL RHEUMATOLOGY | 2014年 / 33卷 / 06期

关键词：

Adult onset Still's disease; Biomarker; Disease activity; Growth arrest-specific protein 6; PLASMA-CONCENTRATIONS; GAS6; PLATELETS; BIOMARKER; LIGANDS; CELLS;

D O I：

10.1007/s10067-014-2629-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We investigated the growth arrest-specific protein 6 in adult-onset Still's disease. Serums were collected from 52 adult-onset Still's disease patients with follow-up samples of 21 patients. The growth arrest-specific protein 6 levels in adult-onset Still's disease were higher compared to those in the normal controls (25.37 +/- 7.71 vs. 19.86 +/- 5.01 ng/mL, p<0.001). However, growth arrest-specific protein 6 did not correlate with disease activity. Also, growth arrest-specific protein 6 was not decreased after activity was resolved in the follow-up. The growth arrest-specific protein 6 in adult-onset Still's disease patients were higher than the normal controls. However, growth arrest-specific protein 6 was not correlated with disease activity.

引用

页码：865 / 868

页数：4

共 20 条

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