Genetics of lens development

被引:0
|
作者
Mglinets, V. A. [1 ]
机构
[1] Med Genet Res Ctr, Moscow 115478, Russia
关键词
neural crest; lens; lens morphogenesis; eye development; placode; signalling; zebrafish; TRANSCRIPTION FACTORS; DISTINCT ROLES; NEURAL PLATE; DIFFERENTIAL EXPRESSION; HOMEOBOX GENE; L-MAF; PAX6; XENOPUS; EYE; MORPHOGENESIS;
D O I
10.1134/S1022795415080050
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The paper discusses the current data on the genetics of the lens development. Genetically based processes of the formation of the lens anlage, as well as its specification and differentiation, are considered. The main genes responsible for these consecutive processes of lens development are presented. Their mutational disorders can lead to the absence or underdevelopment of the lens or multiple types of cataracts.
引用
收藏
页码:939 / 948
页数:10
相关论文
共 50 条
  • [31] Apoptosis in lens development and pathology
    Yan, Qin
    Liu, Jin-Ping
    Li, David Wan-Cheng
    DIFFERENTIATION, 2006, 74 (05) : 195 - 211
  • [32] Teleost lens development and degeneration
    Vihtelic, Thomas S.
    INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY, VOL 269, 2008, 269 : 341 - 373
  • [33] Connexins in lens development and cataractogenesis
    Gong, Xiaohua
    Cheng, Catherine
    Xia, Chun-hong
    JOURNAL OF MEMBRANE BIOLOGY, 2007, 218 (1-3) : 9 - 12
  • [34] Integrins in lens development and disease
    Walker, Janice
    Menko, A. Sue
    EXPERIMENTAL EYE RESEARCH, 2009, 88 (02) : 216 - 225
  • [35] Genetics Underlying the Interactions between Neural Crest Cells and Eye Development
    Weigele, Jochen
    Bohnsack, Brenda L.
    JOURNAL OF DEVELOPMENTAL BIOLOGY, 2020, 8 (04) : 1 - 24
  • [36] Zebrafish mab21l2 mutants possess severe defects in optic cup morphogenesis, lens and cornea development
    Gath, Natalie
    Gross, Jeffrey M.
    DEVELOPMENTAL DYNAMICS, 2019, 248 (07) : 514 - 529
  • [37] Systems biology of lens development: A paradigm for disease gene discovery in the eye
    Ahand, Deepti
    Lachke, Salil A.
    EXPERIMENTAL EYE RESEARCH, 2017, 156 : 22 - 33
  • [38] Crim1 regulates integrin signaling in murine lens development
    Zhang, Ying
    Fan, Jieqing
    Ho, Joshua W. K.
    Hu, Tommy
    Kneeland, Stephen C.
    Fan, Xueping
    Xi, Qiongchao
    Sellarole, Michael A.
    de Vries, Wilhelmine N.
    Lu, Weining
    Lachke, Salil A.
    Lang, Richard A.
    John, Simon W. M.
    Maas, Richard L.
    DEVELOPMENT, 2016, 143 (02): : 356 - 366
  • [39] Control of lens development by Lhx2-regulated neuroretinal FGFs
    Thein, Thuzar
    de Melo, Jimmy
    Zibetti, Cristina
    Clark, Brian S.
    Juarez, Felicia
    Juarez, Felicia
    Blackshaw, Seth
    DEVELOPMENT, 2016, 143 (21): : 3994 - 4002
  • [40] Identification of lens-regulated genes driving anterior eye development
    Liu, Yanlin
    Shamsi, Sadia
    Shaw, Sophie
    Collie-Duguid, Elaina
    Herrera, Eloisa
    Collinson, J. Martin
    Vargesson, Neil
    Erskine, Lynda
    DEVELOPMENTAL BIOLOGY, 2025, 520 : 91 - 107