Genetics of lens development

被引:0
|
作者
Mglinets, V. A. [1 ]
机构
[1] Med Genet Res Ctr, Moscow 115478, Russia
关键词
neural crest; lens; lens morphogenesis; eye development; placode; signalling; zebrafish; TRANSCRIPTION FACTORS; DISTINCT ROLES; NEURAL PLATE; DIFFERENTIAL EXPRESSION; HOMEOBOX GENE; L-MAF; PAX6; XENOPUS; EYE; MORPHOGENESIS;
D O I
10.1134/S1022795415080050
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The paper discusses the current data on the genetics of the lens development. Genetically based processes of the formation of the lens anlage, as well as its specification and differentiation, are considered. The main genes responsible for these consecutive processes of lens development are presented. Their mutational disorders can lead to the absence or underdevelopment of the lens or multiple types of cataracts.
引用
收藏
页码:939 / 948
页数:10
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