Efficient Niementowski synthesis of novel derivatives of 1,2,9,11-tetrasubstituted-7H-thieno[2′,3′:4,5]pyrimido[6,1-b]-quinazolin-7-one

被引：0

作者：

Laddha, Sachin S. ^{[1
]}

Bhatnagar, Satayendra P. ^{[1
]}

机构：

[1] Birla Inst Technol, Dept Pharmaceut Sci, Ranchi 835215, Bihar, India

来源：

ARKIVOC | 2008年

关键词：

Sulphur heterocycles; fused thieno[2,3-d]pyrimidine; cyclization; microwave assisted synthesis;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Starting from 5,6-disubstituted-3H-thieno[2,3-d]pyrimidin-4-ones, novel 1,2,9,11-tetrasubstituted-7H-thieno[2',3':4,5]pyrimido[6,1-b]quinazolin-7-ones could be reached in two steps through a von Niementowski reaction, which involves condensation of substituted anthranilic acids with a 4-chloro-5,6-disubstituted-3H-thieno[2,3-d]pyrimidines. Microwave irradiation in acetic acid media was used in order to improve reactions where conventional heating was limited

引用

页码：212 / 220

页数：9

共 38 条

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