The rational design and evaluation of a peptide inhibitor of the PD-1/PD-L1 interaction

被引：0
|
作者：
Boohaker, Rebecca J. [1 ]
Sambandam, Vijaya [1 ]
Suto, Mark [1 ]
Xu, Bo [1 ]
机构：
[1] Southern Res Inst, Birmingham, AL 35255 USA
来源：
CANCER RESEARCH | 2018年 / 78卷 / 13期
关键词：
D O I：
10.1158/1538-7445.AM2018-5668
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
5668
引用
收藏
页数：2
相关论文
共 50 条
  • [21] In vitro characterization of a small molecule PD-1 inhibitor that targets the PD-l/PD-L1 interaction
    Chih-Hao Lu
    Wei-Min Chung
    Chun-Hao Tsai
    Ju-Chien Cheng
    Kai-Cheng Hsu
    Huey-En Tzeng
    Scientific Reports, 12
  • [22] Evaluation of PD-L1 and PD-1 in Colorectal Polyps
    Mostafa, Mohamed
    Hartley, Christopher
    Mackinnon, Alexander
    Hagen, Catherine
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2016, 146 : S135 - S135
  • [23] Design, Synthesis, and Biological Evaluation of Imidazopyridines as PD-1/PD-L1 Antagonists
    Butera, Roberto
    Wazynska, Marta
    Magiera-Mularz, Katarzyna
    Plewka, Jacek
    Musielak, Bogdan
    Surmiak, Ewa
    Sala, Dominik
    Kitel, Radoslaw
    de Bruyn, Marco
    Nijman, Hans W.
    Elsinga, Philip H.
    Holak, Tad A.
    Domling, Alexander
    ACS MEDICINAL CHEMISTRY LETTERS, 2021, 12 (05): : 768 - 773
  • [24] PD-1/PD-L1 Inhibitor Plus Chemotherapy Versus PD-1/PD-L1 Inhibitor in Microsatellite Instability Gastrointestinal Cancers: A Multicenter Retrospective Study
    Chen, Mifen
    Wang, Zhenghang
    Liu, Zimin
    Deng, Ting
    Wang, Xiaodong
    Chang, Zhiwei
    Zhang, Qi
    Yang, Wenlei
    Liu, Ning
    Ji, Zhi
    Zhang, Xiaotian
    Wang, Xicheng
    Peng, Zhi
    Li, Yi
    Cao, Yujuan
    Jin, Xuan
    Lu, Hongxia
    Qu, Huajun
    Tang, Yong
    Xu, Chunlei
    Fang, Weijia
    Zhang, Hangyu
    Yan, Dong
    Wang, Li
    Li, Jiayi
    Zhang, Jingdong
    Wang, Qiwei
    Xue, Liying
    Yin, Fei
    Han, Guangjie
    Cheng, Zhiqiang
    Liu, Qing
    Jin, Yongdong
    Zhang, Yinjie
    Li, Lanxing
    Cao, Baoshan
    Yao, Yanhong
    Chen, Zhiyu
    Zou, Jianling
    Ying, Jieer
    Wei, Qing
    Tian, Tiantian
    Zhao, Weifeng
    Li, Longmei
    Zhang, Tong
    Song, Fanghua
    Ba, Ya-er
    Li, Na
    Gao, Hui
    Ji, Yinghua
    JCO PRECISION ONCOLOGY, 2023, 7
  • [25] Discovery of hPRDX5-based peptide inhibitors blocking PD-1/PD-L1 interaction through in silico proteolysis and rational design
    Zou, Sen
    Liu, Juanjuan
    Sun, Zhengyang
    Feng, Xiao
    Wang, Zhongbo
    Jin, Yuanyuan
    Yang, Zhaoyong
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2020, 85 (01) : 185 - 193
  • [26] Discovery of hPRDX5-based peptide inhibitors blocking PD-1/PD-L1 interaction through in silico proteolysis and rational design
    Sen Zou
    Juanjuan Liu
    Zhengyang Sun
    Xiao Feng
    Zhongbo Wang
    Yuanyuan Jin
    Zhaoyong Yang
    Cancer Chemotherapy and Pharmacology, 2020, 85 : 185 - 193
  • [27] Targeting the PD-1/PD-L1 interaction in nasopharyngeal carcinoma
    Johnson, David
    Ma, Brigette B. Y.
    ORAL ONCOLOGY, 2021, 113
  • [28] Miniprotein engineering for inhibition of PD-1/PD-L1 interaction
    Ciesiolkiewicz, Agnieszka
    Perez, Juan Lizandra
    Skalniak, Lukasz
    Nocen, Pawel
    Berlicki, Lukasz
    PROTEIN SCIENCE, 2024, 33 (08)
  • [29] PD-1/PD-L1 inhibitors
    Sunshine, Joel
    Taube, Janis M.
    CURRENT OPINION IN PHARMACOLOGY, 2015, 23 : 32 - 38
  • [30] PD-1/PD-L1 in disease
    Kuol, Nyanbol
    Stojanovska, Lily
    Nurgali, Kulmira
    Apostolopoulos, Vasso
    IMMUNOTHERAPY, 2018, 10 (02) : 149 - 161
12345