The calcium-parathyroid hormone regulation in chronic renal failure investigation of its dynamic secretion pattern

被引：5
|
作者：
Heidbreder, E [1 ]
Naujoks, H [1 ]
Brosa, U [1 ]
Schramm, L [1 ]
机构：
[1] BROSA GMBH,AMONEBURG,GERMANY
来源：
HORMONE AND METABOLIC RESEARCH | 1997年 / 29卷 / 02期
关键词：
parathyroid hormone secretion; hyperparathyroidism; chronic renal failure; hypocalcemia; hypercalcemia;
D O I：
10.1055/s-2007-978989
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In patients with secondary hyperparathyroidism (HPT) caused by chronic renal failure (CRF), the pulsatility of parathyroid hormone (PTH) secretion and the relation of PTH to plasma Ca2+ concentrations were investigated. Intermittent hyper- and hypocalcemia was induced to study the deterministic reaction of the parathyroid glands. Compared to normal behaviour in CRF the pulsatility is lost. Yet the deterministic coupling between PTH and Ca2+ concentrations remains qualitatively the same though quantitatively it is exaggerated and varies depending on the subjects.
引用
收藏
页码：70 / 75
页数：6
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