Otosclerosis: etiopathogenesis and histopathology

被引：30
作者：
Cureoglu, Sebahattin
Schachern, Patricia A.
Ferlito, Alfio
Rinaldo, Alessandra
Tsuprun, Vladimir
Paparella, Michael M.
机构：
[1] Univ Udine, Policlin Univ, ENT Clin, Dept Surg Sci, I-33100 Udine, Italy
[2] Univ Minnesota, Dept Otolaryngol, Minneapolis, MN USA
来源：
AMERICAN JOURNAL OF OTOLARYNGOLOGY | 2006年 / 27卷 / 05期
关键词：
D O I：
10.1016/j.amjoto.2005.11.001
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
Otosclerosis is a disease of the bony labyrinth manifesting clinically as a progressive conductive hearing loss, a mixed-type hearing loss, or a sensorineural hearing loss. The age of onset of the hearing loss caused by otosclerosis is principally between 15 and 40 years. Although histopathological inner ear changes due to otosclerosis have been very well documented, the true etiopathogenesis of the disease has yet to be described despite intensive research. Both genetic and environmental factors have been implicated, however. (C) 2006 Elsevier Inc. All rights reserved.
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页码：334 / 340
页数：7
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