Microfluidics and cancer analysis: cell separation, cell/tissue culture, cell mechanics, and integrated analysis systems

被引:23
作者
Pappas, Dimitri [1 ]
机构
[1] Texas Tech Univ, Dept Chem & Biochem, Lubbock, TX 79409 USA
关键词
CIRCULATING TUMOR-CELLS; MICROVASCULAR NETWORKS; IMMOBILIZED APTAMERS; NEGATIVE ENRICHMENT; GRADIENTS; GENERATION; DEVICE; BLOOD; ARRAY; TECHNOLOGY;
D O I
10.1039/c5an01778e
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Among the growing number of tools available for cancer studies, microfluidic systems have emerged as a promising analytical tool to elucidate cancer cell and tumor function. Microfluidic methods to culture cells have created approaches to provide a range of environments from single-cell analysis to complex three-dimensional devices. In this review we discuss recent advances in tumor cell culture, cancer cell analysis, and advanced studies enabled by microfluidic systems.
引用
收藏
页码:525 / 535
页数:11
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