Variables associated with self-reported anxiety and depression symptoms in patients with chronic myeloid leukemia receiving tyrosine kinase inhibitor therapy

被引：19

作者：

Shi, Dayu ^{[1
]}

Li, Zongru ^{[1
]}

Li, Yongjie ^{[2
]}

Jiang, Qian ^{[1
,3
]}

机构：

[1] Peking Univ, Inst Hematol, Peoples Hosp, 11 Xizhimen South St, Beijing 100044, Peoples R China

[2] Peking Univ, Peoples Hosp, Dept Neurol, Beijing 100044, Peoples R China

[3] Soochow Univ, Collaborat Innovat Ctr Hematol, Suzhou, Peoples R China

来源：

LEUKEMIA & LYMPHOMA | 2021年 / 62卷 / 03期

基金：

中国国家自然科学基金;

关键词：

Chronic myeloid leukemia; anxiety; depression; tyrosine kinase inhibitor; QUALITY-OF-LIFE; 1ST-LINE TREATMENT; IMATINIB; OUTCOMES; HEALTH; CHINESE; RECOMMENDATIONS;

D O I：

10.1080/10428194.2020.1842397

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Variables associated with self-reported anxiety and depression symptoms were explored in 1169 adults with chronic myeloid leukemia (CML) receiving tyrosine kinase inhibitor (TKI)-therapy. The Self-Rating Anxiety Scale and Self-Rating Depression Scale questionnaires were used to measure anxiety and depression symptoms. Two hundred and fifty-one (22.4%) and 415 (37.1%) respondents reported anxiety and depression, respectively. In multivariate analyses, female sex, lower education level, comorbidities, advanced-line TKI-therapy, and longer TKI-therapy duration were significantly associated with more severe anxiety and/or depression. It is concluded that socio-demographics, comorbidities, advanced-line TKI-therapy, and longer TKI-therapy duration were significantly associated with anxiety and/or depression symptoms in CML patients receiving TKI-therapy.

引用

页码：640 / 648

页数：9

共 45 条

[1] Assessment of quality of life with imatinib mesylate as first-line treatment in chronic phase-chronic myeloid leukemia [J].

Aziz, Zeba ;

Iqbal, Javaid ;

Aaqib, Muhammad ;

Akram, Muhammad ;

Saeed, Asif .

LEUKEMIA & LYMPHOMA, 2011, 52 (06) :1017-1023

[2] European LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013 [J].

Baccarani, Michele ;

Deininger, Michael W. ;

Rosti, Gianantonio ;

Hochhaus, Andreas ;

Soverini, Simona ;

Apperley, Jane F. ;

Cervantes, Francisco ;

Clark, Richard E. ;

Cortes, Jorge E. ;

Guilhot, Francois ;

Hjorth-Hansen, Henrik ;

Hughes, Timothy P. ;

Kantarjian, Hagop M. ;

Kim, Dong-Wook ;

Larson, Richard A. ;

Lipton, Jeffrey H. ;

Mahon, Francois-Xavier ;

Martinelli, Giovanni ;

Mayer, Jiri ;

Mueller, Martin C. ;

Niederwieser, Dietger ;

Pane, Fabrizio ;

Radich, Jerald P. ;

Rousselot, Philippe ;

Saglio, Giuseppe ;

Saussele, Susanne ;

Schiffer, Charles ;

Silver, Richard ;

Simonsson, Bengt ;

Steegmann, Juan-Luis ;

Goldman, John M. ;

Hehlmann, Ruediger .

BLOOD, 2013, 122 (06) :872-884

[3] Recommendations for Incorporating Patient-Reported Outcomes Into Clinical Comparative Effectiveness Research in Adult Oncology [J].

Basch, Ethan ;

Abernethy, Amy P. ;

Mullins, C. Daniel ;

Reeve, Bryce B. ;

Smith, Mary Lou ;

Coons, Stephen Joel ;

Sloan, Jeff ;

Wenzel, Keith ;

Chauhan, Cynthia ;

Eppard, Wayland ;

Frank, Elizabeth S. ;

Lipscomb, Joseph ;

Raymond, Stephen A. ;

Spencer, Merianne ;

Tunis, Sean .

JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (34) :4249-4255

[4] Life Expectancy of Patients With Chronic Myeloid Leukemia Approaches the Life Expectancy of the General Population [J].

Bower, Hannah ;

Bjorkholm, Magnus ;

Dickman, Paul W. ;

Hoglund, Martin ;

Lambert, Paul C. ;

Andersson, Therese M. -L. .

JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (24) :2851-+

[5] Factors associated with anxiety and depressive symptoms in colorectal cancer survivors [J].

Braamse, Annemarie M. J. ;

van Turenhout, Sietze T. ;

Droste, Jochim S. Terhaar Sive ;

de Groot, Gerrit H. ;

van der Hulst, Rene W. M. ;

Klemt-Kropp, Michael ;

Kuiken, Sjoerd D. ;

Loffeld, Ruud J. L. F. ;

Uiterwaal, M. Tessa ;

Mulder, Chris J. J. ;

Dekker, Joost .

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 2016, 28 (07) :831-835

[6] Anxiety and depression in patients with Philadelphia-negative myeloproliferative neoplasms: a nationwide population-based survey in Denmark [J].

Brochmann, Nana ;

Flachs, Esben Meulengracht ;

Christensen, Anne Illemann ;

Bak, Marie ;

Andersen, Christen Lykkegaard ;

Juel, Knud ;

Hasselbalch, Hans Carl ;

Zwisler, Ann-Dorthe ;

Rottmann, Nina .

CLINICAL EPIDEMIOLOGY, 2019, 11 :23-33

[7] Front-Line and Salvage Therapies With Tyrosine Kinase Inhibitors and Other Treatments in Chronic Myeloid Leukemia [J].

Cortes, Jorge ;

Hochhaus, Andreas ;

Hughes, Timothy ;

Kantarjian, Hagop .

JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (05) :524-531

[8] Final 5-Year Study Results of DASISION: The Dasatinib Versus Imatinib Study in Treatment-Naive Chronic Myeloid Leukemia Patients Trial [J].

Cortes, Jorge E. ;

Saglio, Giuseppe ;

Kantarjian, Hagop M. ;

Baccarani, Michele ;

Mayer, Jiri ;

Boque, Concepcion ;

Shah, Neil P. ;

Chuah, Charles ;

Casanova, Luis ;

Bradley-Garelik, Brigid ;

Manos, George ;

Hochhaus, Andreas .

JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (20) :2333-U54

[9] CLINICAL AND PUBLIC-HEALTH PERSPECTIVES AND APPLICATIONS OF HEALTH-RELATED QUALITY-OF-LIFE MEASUREMENT [J].

EBRAHIM, S .

SOCIAL SCIENCE & MEDICINE, 1995, 41 (10) :1383-1394

[10] Health-Related Quality of Life in Patients With Chronic Myeloid Leukemia Receiving First-Line Therapy With Nilotinib [J].

Efficace, Fabio ;

Castagnetti, Fausto ;

Martino, Bruno ;

Breccia, Massimo ;

D'Adda, Mariella ;

Angelucci, Emanuele ;

Stagno, Fabio ;

Cottone, Francesco ;

Malato, Alessandra ;

Trabacchi, Elena ;

Capalbo, Silvana Franca ;

Gobbi, Marco ;

Visani, Giuseppe ;

Salvucci, Marzia ;

Capodanno, Isabella ;

Tosi, Patrizia ;

Tiribelli, Mario ;

Scortechini, Anna Rita ;

Levato, Luciano ;

Maino, Elena ;

Binotto, Gianni ;

Gugliotta, Gabriele ;

Vignetti, Marco ;

Baccarani, Michele ;

Rosti, Gianantonio .

CANCER, 2018, 124 (10) :2228-2237

← 1 2 3 4 5 →