Inflammatory epidermolysis bullosa acquisita in a 4-year-old girl

被引:6
作者
Lazic-Mosler, Elvira [1 ,2 ]
Jukic, Ines Lakos [3 ,4 ]
Murat-Susic, Slobodna [3 ,4 ]
Husar, Karmela [3 ,4 ]
Skerlev, Mihael [3 ,4 ]
Bukvic Mokos, Zrinka [3 ,4 ]
Ishii, Norito [5 ,6 ]
Hashimoto, Takashi [5 ,6 ]
Marinovic, Branka [3 ,4 ]
机构
[1] Gen Hosp Dr Ivo Pedis, Dept Dermatol & Venereol, Sisak, Croatia
[2] Univ Zagreb, Sch Med, Dept Anat, Zagreb 41001, Croatia
[3] Univ Hosp Ctr Zagreb, Univ Dept Dermatol & Venereol, Zagreb 10000, Croatia
[4] Univ Zagreb, Sch Med, Zagreb 41001, Croatia
[5] Kurume Univ, Sch Med, Dept Dermatol, Kurume, Fukuoka 830, Japan
[6] Kurume Univ, Inst Cutaneous Cell Biol, Kurume, Fukuoka 830, Japan
关键词
acquired epidermolysis bullosa; bullous skin disease; childhood blistering; epidermolysis bullosa aquisita antigen; inflammatory epidermolysis bullosa aquisita; VII COLLAGEN; AUTOANTIBODIES; ANTIGEN; DOMAINS;
D O I
10.1111/1346-8138.12958
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
This study presents a case of linear immunoglobulin A dermatosis-like epidermolysis bullosa acquisita in a 4-year-old girl showing rapid, widespread and inflammatory skin lesions. The diagnosis was confirmed by histopathology, direct and indirect immunofluorescence, various immunoblotting analyses and enzyme-linked immunosorbent assays. Despite the severe clinical manifestations, the disease was successfully controlled by combination therapy of oral prednisolone and dapsone.
引用
收藏
页码:1098 / 1100
页数:3
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