Treatment and prognosis of mature (non-anaplastic) T- and NK-cell lymphomas in childhood, adolescents, and young adults

被引:3
作者
Xavier, Ana C. [1 ]
Suzuki, Ritsuro [2 ]
机构
[1] Univ Alabama Birmingham, Childrens Alabama, Dept Pediat, Div Hematol Oncol, Birmingham, AL USA
[2] Shimane Univ Hosp, Dept Haematol Oncol, Izumo, Shimane, Japan
关键词
paediatrics; non-Hodgkin lymphoma; peripheral T-cell lymphoma; extranodal NK-T-cell lymphoma; stem cell transplantation; EPSTEIN-BARR-VIRUS; UNITED-KINGDOM; L-ASPARAGINASE; LYMPHOPROLIFERATIVE DISEASE; CLINICOPATHOLOGICAL ENTITY; RETROSPECTIVE ANALYSIS; ISOCHROMOSOME; 7Q; ADVANCED-STAGE; PD1; BLOCKADE; PHASE-II;
D O I
10.1111/bjh.15772
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Paediatric non-Hodgkin lymphomas (pNHL) are a diverse group of malignancies characterised by nodal and/or extranodal involvement. Less common pNHL forms include those derived from mature T- and natural killer (NK) cells. Much of our current understanding of paediatric mature (non-anaplastic) T/NK-cell lymphomas with respect to pathogenesis, diagnosis and treatment is extrapolated from adult literature. At the Sixth International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkin Lymphoma, convened September 26-29, 2018 in Rotterdam, The Netherlands, some important aspects on diagnosis and outcomes of mature (non-anaplastic) T/NK-cell lymphoma in children and adolescents were discussed and will be reviewed in here.
引用
收藏
页码:1086 / 1098
页数:13
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