Development of a donor-acceptor concept for enzymatic cross-coupling reactions of aldehydes:: The first asymmetric cross-benzoin condensation

被引:194
作者
Dünkelmann, P
Kolter-Jung, D
Nitsche, A
Demir, AS
Siegert, P
Lingen, B
Baumann, M
Pohl, M
Müller, M
机构
[1] Forschungszentrum, Inst Biotechnol 2, D-52425 Julich, Germany
[2] Univ Dusseldorf, Inst Enzyme Technol, D-4000 Dusseldorf, Germany
关键词
D O I
10.1021/ja0271476
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Highly enantioenriched mixed benzoins are obtained selectively through a biocatalytical cross-coupling reaction of aromatic aldehydes using ThDP-dependent enzymes. Copyright © 2002 American Chemical Society.
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页码:12084 / 12085
页数:2
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