Acute transverse myelitis of childhood due to novel coronavirus disease 2019: The first pediatric case report and review of literature

被引:22
作者
Nejad Biglari, Habibeh [1 ]
Sinaei, Reza [2 ,3 ]
Pezeshki, Sara [3 ]
Khajeh Hasani, Fatemeh [4 ]
机构
[1] Kerman Univ Med Sci, Neurosci Res Ctr, Inst Neuropharmacol, Pediat Neurol, Kerman, Iran
[2] Kerman Univ Med Sci, Dept Pediat, Pediat Rheumatol, Kerman, Iran
[3] Kerman Univ Med Sci, Inst Basic & Clin Physiol Sci, Endocrinol & Metab Res Ctr, Kerman, Iran
[4] Kerman Univ Med Sci, Sch Med, Dept Radiol, Kerman, Iran
关键词
Transverse Myelitis; Neuromyelitis Optica; COVID-19;
D O I
10.22037/ijcn.v15i1.31579
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The global coronavirus disease 2019 (COVID-19) pandemic appears to have some streaks of severity in pediatrics. These streaks include variable signs of respiratory distress, a new entity called multi-system inflammatory syndrome, and some evidences of neurological symptoms involving both central and peripheral nervous systems. Here, we described the first pediatric patient with COVID-19 who presented with acute transverse myelitis. An 11-year-old otherwise healthy girl presented to our clinic with acute onset of lower limbs paresis, urinary and fecal retention, alongside epigastric pain, and fever for 3 days. A neurological examination revealed a severe flaccid paraplegia in her lower limbs associated with a sensory level at T5. She was evaluated systematically for all probable causes of her symptoms, and finally, due to having a positive nasopharyngeal PCR test, she was considered to suffer from post-COVID-19 transverse myelitis. She underwent intravenous-immunoglobulin, methylprednisolone pulse, and other supportive cares without obvious results. Therefore, she underwent seven sessions of plasma exchange with little effects on muscle strength. The focal inflammation and injury of the spinal cord, otherwise known as transverse myelitis, have a wide array of potential etiologies. Transverse myelitis has been well documented to be the result of viral and bacterial infections. We believe our patient was not involved in a cytokine storm status due to good CRP, IL-6 and Ferritin levels. Albeit, we cannot certainly consider the patient to have a direct viral impact or involved in a late immunity process. To our knowledge, this is the first report of TM in the field of pediatrics occurred after COVID-19. Thus, this is critical to note that children can present with some severe types of COVID-19.
引用
收藏
页码:107 / 112
页数:6
相关论文
共 50 条
[11]   Rhabdomyolysis and coronavirus disease-2019 in children: A case report and review of the literature [J].
Kontou Maria ;
Kakleas Konstantinos ;
Kimioni Vaso ;
Georgiadi Dimitra ;
Spoulou Vasiliki ;
Michos Athanasios .
儿科学研究(英文), 2022, 06 (02) :135-139
[12]   A First Case of Acute Cerebellitis Associated with Coronavirus Disease (COVID-19): a Case Report and Literature Review [J].
Fadakar, Nima ;
Ghaemmaghami, Sara ;
Masoompour, Seyed Masoom ;
Yeganeh, Babak Shirazi ;
Akbari, Ali ;
Hooshmandi, Sedighe ;
Ostovan, Vahid Reza .
CEREBELLUM, 2020, 19 (06) :911-914
[13]   A First Case of Acute Cerebellitis Associated with Coronavirus Disease (COVID-19): a Case Report and Literature Review [J].
Nima Fadakar ;
Sara Ghaemmaghami ;
Seyed Masoom Masoompour ;
Babak Shirazi Yeganeh ;
Ali Akbari ;
Sedighe Hooshmandi ;
Vahid Reza Ostovan .
The Cerebellum, 2020, 19 :911-914
[14]   ACUTE TRANSVERSE MYELITIS ASSOCIATED WITH MYCOPLASMA-PNEUMONIAE INFECTION - A CASE-REPORT AND REVIEW OF THE LITERATURE [J].
MILLS, RW ;
SCHOOLFIELD, L .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1992, 11 (03) :228-231
[15]   Unilateral acute central serous chorioretinopathy with inactivated coronavirus disease 2019 vaccination: A case report and review of literature [J].
Abrishami, Mojtaba ;
Hosseini, Seyedeh ;
Shoeibi, Nasser ;
Heidarzadeh, Hamid .
JOURNAL OF CURRENT OPHTHALMOLOGY, 2022, 34 (03) :373-378
[16]   Transverse myelitis, a rare neurological manifestation of mixed connective tissue disease—a case report and a review of literature [J].
Sumeet Bhinder ;
Kevin Harbour ;
Vikas Majithia .
Clinical Rheumatology, 2007, 26 :445-447
[17]   Transverse myelitis, a rare neurological manifestation of mixed connective tissue disease - a case report and a review of literature [J].
Bhinder, Sumeet ;
Harbour, Kevin ;
Majithia, Vikas .
CLINICAL RHEUMATOLOGY, 2007, 26 (03) :445-447
[18]   Longitudinally Extensive Transverse Myelitis in a Patient With Systemic Lupus Erythematosus: A Case Report and Literature Review [J].
Banjade, Prakash ;
Bastakoti, Sudip ;
Poudel, Ashmita ;
Sharma, Munish .
CUREUS JOURNAL OF MEDICAL SCIENCE, 2024, 16 (08)
[19]   Fatal arrhythmia associated with novel coronavirus 2019 infection: Case report and literature review [J].
Shu, Hongyun ;
Li, Qiaowen ;
Zhang, Xiaoyong ;
Zhao, Guojun ;
Cui, Yaqian ;
Zhu, Xiyan .
MEDICINE, 2024, 103 (16) :E37894
[20]   Association of Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease with Coronavirus Disease 2019 Vaccination and Infection: A Case Report of Cortical Encephalitis and Transverse Myelitis Relapse [J].
Himeno, Yohei ;
Tateishi, Takahisa ;
Irie, Ken-Ichi ;
Ueno, Shuntaro ;
Morimitsu, Makoto ;
Mizoguchi, Shino ;
Koga, Tamon ;
Taniwaki, Takayuki .
INTERNAL MEDICINE, 2023, 62 (23) :3549-3554