Essential oil antibacterial activity against methicillin-resistant and -susceptible Staphylococcus aureus strains

被引:14
作者
Bona, Elisa [1 ]
Massa, Nadia [2 ]
Novello, Giorgia [2 ]
Pavan, Matteo [2 ]
Rocchetti, Andrea [3 ]
Berta, Graziella [2 ]
Gamalero, Elisa [2 ]
机构
[1] Univ Piemonte Orientale, Dipartimento Sci Innovaz Tecnol, Vercelli, Italy
[2] Univ Piemonte Orientale, Dipartimento Sci Innovaz Tecnol, Alessandria, Italy
[3] Azienda Sanit Santi Antonio Biagio & Cesare Arrig, Alessandria, Italy
关键词
Staphylococcus aureus; essential oils; minimal inhibitory concentration; disk diffusion; fluorescein diacetate assay; TEA TREE OIL; TIME-KILL; CARVACROL; BIOFILM; L;
D O I
10.4081/mr.2019.8331
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Staphylococcus aureus is a pathogen causing infections that range from skin lesions to life threatening conditions. Methicillin resistance development in S. aureus strains represents a huge problem worldwide. The inhibition efficacy of twelve different essential oils (laurel, anise, oregano, basil, lavender, mint, rosemary, tea tree, bergamot, grapefruit, ginger and winter savory) and of the antibiotic Vancomycin was tested against S. aureus NCTC6571 and clinical isolates using paper disk diffusion assay and broth microdilution test methods. Forty-four S. aureus s trains isolated from different human sample were characterized for antibiotic resistance and 41% of them were methicillin resistant. Among the twelve tested oils basil, oregano and savory showed stronger inhibition effect on S. aureus growth than Vancomycin. These results can be useful for the formulation of topical gel containing selected essential oils active against S. aureus strains.
引用
收藏
页码:31 / 38
页数:8
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