Methyl 2-((succinimidooxy)carbonyl)benzoate (MSB):: A new, efficient reagent for N-phthaloylation of amino acid and peptide derivatives

被引：34
作者：
Casimir, JR [1 ]
Guichard, G [1 ]
Briand, JP [1 ]
机构：
[1] IBMC, Lab Immunol & Chim Therapeut, UPR 9021, CNRS, F-67084 Strasbourg, France
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2002年 / 67卷 / 11期
关键词：
D O I：
10.1021/jo016347h
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new, efficient, and readily available reagent, methyl 2-((succinimidooxy)carbonyl)benzoate (MSB), for N-phthaloylation of amino acids and amino acid derivatives is described. The phthaloylation procedure is simple and racemization-free and gives excellent results with a-amino acids, a-amino alcohols, dipeptides, alpha-amino carboxamides, and alpha-amino esters.
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页码：3764 / 3768
页数：5
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