Methylation of mitochondrial DNA is not a useful marker for cancer detection

被引：53

作者：

Maekawa, M ^{[1
]}

Taniguchi, T

Higashi, H

Sugimura, H

Sugano, K

Kanno, T

机构：

[1] Hamamatsu Univ Sch Med, Dept Lab Med, Hamamatsu, Shizuoka 4313192, Japan

[2] Hamamatsu Univ Sch Med, Dept Pathol 1, Hamamatsu, Shizuoka 4313192, Japan

[3] Tochigi Canc Ctr, Res Inst, Canc Prevent Unit, Oncogene Res Unit, Utsunomiya, Tochigi, Japan

来源：

CLINICAL CHEMISTRY | 2004年 / 50卷 / 08期

关键词：

D O I：

10.1373/clinchem.2004.035139

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

引用

页码：1480 / 1481

页数：2

共 6 条

[1]

Baylin SB, 1998, ADV CANCER RES, V72, P141

[2] PERVASIVE CPG SUPPRESSION IN ANIMAL MITOCHONDRIAL GENOMES [J].

CARDON, LR ;

BURGE, C ;

CLAYTON, DA ;

KARLIN, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (09) :3799-3803

[3] Facile detection of mitochondrial DNA mutations in tumors and bodily fluids [J].

Fliss, MS ;

Usadel, H ;

Cabellero, OL ;

Wu, L ;

Buta, MR ;

Eleff, SM ;

Jen, J ;

Sidransky, D .

SCIENCE, 2000, 287 (5460) :2017-2019

[4] Heterogeneity of DNA methylation status analyzed by bisulfite-PCR-SSCP and correlation with clinico-pathological characteristics in colorectal cancer [J].

Maekawa, M ;

Sugano, K ;

Ushiama, M ;

Fukayama, N ;

Nomoto, K ;

Kashiwabara, H ;

Fujita, S ;

Kakizoe, T .

CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2001, 39 (02) :121-128

[5] Mitochondrial mutagenesis in human cells and tissues [J].

Marcelino, LA ;

Thilly, WG .

MUTATION RESEARCH-DNA REPAIR, 1999, 434 (03) :177-203

[6]

REIS RJS, 1983, J BIOL CHEM, V258, P9078

← 1 →