Childhood empyema: Limited potential impact of 7-valent pneumococcal conjugate vaccine

被引:48
作者
Fletcher, M
Leeming, J
Cartwright, K
Finn, A
机构
[1] Univ Bristol, Dept Clin Sci S Bristol, Inst Child Life & Hlth, UBHT Educ Ctr, Bristol BS2 8AE, Avon, England
[2] Univ W England, Fac Hlth & Social Care, Bristol BS16 1QY, Avon, England
[3] Bristol Royal Infirm & Gen Hosp, Hlth Protect Agcy, SW Reg Lab, Bristol, Avon, England
关键词
empyema; capsular polysaccharide; ELISA; diagnosis;
D O I
10.1097/01.inf.0000219535.14201.1b
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
During 2003-2004, locally presenting pleural empyema cases in children increased 3-fold. Antigen analysis of empyema fluid identified Streptococcus pneumoniae in 27 of 29 cases for whom samples were available and capsular polysaccharide type I in 18 of these. Use of a conjugate vaccine without serotype I antigen would have had limited impact on this morbidity in our region.
引用
收藏
页码:559 / 560
页数:2
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