Thermal degradation of peptides and formation of acrylamide

被引：14

作者：

Buhlert, Juergen

Carle, Reinhold

Majer, Zsuzsa

Spitzner, Dietrich

机构：

[1] Chem & Vet Untersuchungsamt Sigmaringen, HPLC LC MS, D-72488 Sigmaringen, Germany

[2] Univ Hohenheim, Inst Lebensmitteltechnol, D-70593 Stuttgart, Germany

[3] Eotvos Lorand Univ, Dept Organ Chem, H-1518 Budapest 112, Hungary

[4] Univ Hohenheim, Inst Chem, D-70593 Stuttgart, Germany

来源：

LETTERS IN ORGANIC CHEMISTRY | 2006年 / 3卷 / 05期

关键词：

acrylamide; peptides; thermolysis;

D O I：

10.2174/157017806776611944

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We describe the formation of acrylamide from alanine containing peptides at 200 degrees C without the assistance of an additional carbonyl compound. This experiment may mimic the formation of acrylamide during the baking of bread.

引用

页码：356 / 357

页数：2

共 8 条

[1]

Bräunling H, 2002, NACHR CHEM, V50, P1386

[2] Acrylamide is formed in the Maillard reaction [J].

Mottram, DS ;

Wedzicha, BL ;

Dodson, AT .

NATURE, 2002, 419 (6906) :448-449

[3] Acrylamide from Maillard reaction products [J].

Stadler, RH ;

Blank, I ;

Varga, N ;

Robert, F ;

Hau, J ;

Guy, PA ;

Robert, MC ;

Riediker, S .

NATURE, 2002, 419 (6906) :449-450

[4] In-depth mechanistic study on the formation of acrylamide and other vinylogous compounds by the Maillard reaction [J].

Stadler, RH ;

Robert, F ;

Riediker, S ;

Varga, N ;

Davidek, T ;

Devaud, S ;

Goldmann, T ;

Hau, J ;

Blank, I .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2004, 52 (17) :5550-5558

[5] Acrylamide:: A cooking carcinogen? [J].

Tareke, E ;

Rydberg, P ;

Karlsson, P ;

Eriksson, S ;

Törnqvist, M .

CHEMICAL RESEARCH IN TOXICOLOGY, 2000, 13 (06) :517-522

[6] Domino reactions in organic synthesis [J].

Tietze, LF .

CHEMICAL REVIEWS, 1996, 96 (01) :115-136

[7] The role of creatine in the generation of N-methylacrylamide: A new toxicant in cooked meat [J].

Yaylayan, VA ;

Locas, CP ;

Wnorowski, A ;

O'Brien, J .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2004, 52 (17) :5559-5565

[8] Why asparagine needs carbohydrates to generate acrylamide [J].

Yaylayan, VA ;

Wnorowski, A ;

Locas, CP .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2003, 51 (06) :1753-1757

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