Prescribing pattern of statins for primary prevention of cardiovascular diseases in patients with type 2 diabetes: insights from Ethiopia

被引:20
作者
Demoz, Gebre Teklemariam [1 ]
Wahdey, Shishay [2 ]
Kasahun, Gebremicheal Gebreslassie [1 ]
Hagazy, Kalay [1 ]
Kinfe, Daniel Gebrehawaria [3 ]
Tasew, Hagos [4 ]
Bahrey, Degena [4 ]
Niriayo, Yirga Legesse [5 ]
机构
[1] Aksum Univ, Coll Hlth Sci, Sch Pharm, POB 298, Aksum, Ethiopia
[2] Mekelle Univ, Sch Publ Hlth, Mekelle, Ethiopia
[3] Aksum Univ, Sch Med, Aksum, Ethiopia
[4] Aksum Univ, Sch Nursing, Aksum, Ethiopia
[5] Mekelle Univ, Sch Pharm, Mekelle, Ethiopia
关键词
MELLITUS; EFFICACY; CARE;
D O I
10.1186/s13104-019-4423-9
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Objective: Although most clinical practice guidelines endorsed statin use in type 2 diabetes (T2D) patients for reducing cardiovascular diseases (CVD), little is known about statin utilization in case of Ethiopia. Hence, this study was aimed to evaluate prescribing pattern of statins for primary prevention of CVD in T2D patients. A retrospective study conducted in T2D patients with the age group of 40-75 years. Prescriptions were audited for details of statin use and dose intensity. Descriptive analysis was performed using SPSS version 22.0. Results: We included a total of 323 study subjects. Of those, 55.7% study subjects were found to be received statin for their primary prevention of CVD. Commonly prescribed type of statins was simvastatin (37.2%), atorvastatin (32.8%) and rosuvastatin (15.6%). Low, moderate and high intensive dose of statins were prescribed in 27.8%, 46.1%, and 26.1%, respectively. Of those subjects received statin, 60.6% had on target cholesterol level. Overall, a significant percentage of subjects did not receive their recommended statin for primary prevention of CVD which is below the guidelines' recommendation. Therefore, adherence to guidelines may help to promote the use of statins for primary prevention of CVD in T2D and advance interventions to improve statin prescribing should be considered.
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页数:7
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