Facile synthesis of (S,S)-1,2-diacylamides and (S,S)-1,2-diamines with C2-symmetry

被引：3

作者：

Ai, Lin ^{[1
]}

Xiao, Jichuan ^{[1
]}

Wang, Guo ^{[1
]}

Shen, Xiumin ^{[1
]}

Zhang, Cong ^{[1
]}

机构：

[1] Beijing Normal Univ, Dept Chem, Beijing 100875, Peoples R China

来源：

SYNTHETIC COMMUNICATIONS | 2006年 / 36卷 / 19期

基金：

中国国家自然科学基金;

关键词：

(S,S)-1,2-diacylamides; (S,S)-1,2-diamines; C-2-symmetry; synthesis;

D O I：

10.1080/00397910600770698

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of chiral vicinal tertiary diacylamides with C-2-symmetry was synthesized from (S)-alpha-phenylethylamine, different aromatic aldehydes, and oxalyl chloride. The diacylamides obtained were then reduced to afford chiral vicinal diamines with C-2-symmetry. We propose that the diacylamides existed in four stable conformational isomers in solution because of the dihedral angle between acylamide bonds.

引用

页码：2859 / 2875

页数：17

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