ZnO-Supported Pd Nanoparticle-Catalyzed Ligand- and Additive-Free Cyanation of Unactivated Aryl Halides Using K4[Fe(CN)6]

被引：54

作者：

Chatterjee, Tanmay ^{[1
]}

Dey, Raju ^{[1
]}

Ranu, Brindaban C. ^{[1
]}

机构：

[1] Indian Assoc Cultivat Sci, Dept Organ Chem, Kolkata 700032, India

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2014年 / 79卷 / 12期

关键词：

MICROWAVE-ASSISTED CYANATION; POTASSIUM HEXACYANOFERRATE(II); ELECTROPHILIC CYANATION; CONVENIENT PROCEDURE; RECYCLABLE CATALYST; THROMBIN INHIBITORS; MEDIATED CYANATION; AROMATIC HALIDES; ROBUST METHOD; OPEN-AIR;

D O I：

10.1021/jo500820q

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The use of a new ZnO-supported palladium(0) nanoparticle catalyst for the cyanation of aryl halides using a relatively benign cyanide source, K-4[Fe(CN)(6)], is described. This catalyst has been applied for the efficient cyanation of a variety of functionalized aryl bromides and activated aryl chlorides. This process circumvents the need for an additive and a ligand for the reaction and offers the advantages of high product yields, low catalyst loading (0.2 mol % Pd), and recyclability of the catalyst.

引用

页码：5875 / 5879

页数：5

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