Are there pulmonary sequelae in patients recovering from COVID-19?

被引:35
|
作者
Rogliani, Paola [1 ,2 ]
Calzetta, Luigino [3 ]
Coppola, Angelo [1 ]
Puxeddu, Ermanno [1 ,2 ]
Sergiacomi, Gianluigi [4 ]
D'Amato, Dejanira [4 ]
Orlacchio, Antonio [5 ,6 ]
机构
[1] Univ Roma Tor Vergata, Dept Expt Med, Resp Med Unit, Via Montpellier 1, I-00133 Rome, Italy
[2] Univ Hosp Policlin Tor Vergata, Div Resp Med, Rome, Italy
[3] Univ Parma, Dept Med & Surg, Resp Dis & Lung Funct Unit, Parma, Italy
[4] Univ Roma Tor Vergata, Dept Diagnost Imaging Mol Imaging Intervent Radio, Rome, Italy
[5] Univ Roma Tor Vergata, Dept Surg Sci, Radiol Unit, Rome, Italy
[6] Univ Hosp Policlin Tor Vergata, Emergency Radiol Unit, Rome, Italy
关键词
COVID-19; Pulmonary fibrosis; HRCT;
D O I
10.1186/s12931-020-01550-6
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
It has been recently hypothesized that infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may lead to fibrotic sequelae in patients recovering from coronavirus disease 2019 (COVID-19). In this observational study, hospitalized patients with COVID-19 had a HRCT of the chest performed to detect the extension of fibrotic abnormalities via Hounsfield Units (HU). At follow-up, the lung density significantly improved in both lungs and in each lobe of all patients, being in the normal range (- 950 to - 700 HU). This study provides preliminary evidence that hospitalized patients with mild-to-moderate forms of COVID-19 are not at risk of developing pulmonary fibrosis.
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页数:4
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