Are there pulmonary sequelae in patients recovering from COVID-19?

被引：35

作者：

Rogliani, Paola ^{[1
,2
]}

Calzetta, Luigino ^{[3
]}

Coppola, Angelo ^{[1
]}

Puxeddu, Ermanno ^{[1
,2
]}

Sergiacomi, Gianluigi ^{[4
]}

D'Amato, Dejanira ^{[4
]}

Orlacchio, Antonio ^{[5
,6
]}

机构：

[1] Univ Roma Tor Vergata, Dept Expt Med, Resp Med Unit, Via Montpellier 1, I-00133 Rome, Italy

[2] Univ Hosp Policlin Tor Vergata, Div Resp Med, Rome, Italy

[3] Univ Parma, Dept Med & Surg, Resp Dis & Lung Funct Unit, Parma, Italy

[4] Univ Roma Tor Vergata, Dept Diagnost Imaging Mol Imaging Intervent Radio, Rome, Italy

[5] Univ Roma Tor Vergata, Dept Surg Sci, Radiol Unit, Rome, Italy

[6] Univ Hosp Policlin Tor Vergata, Emergency Radiol Unit, Rome, Italy

来源：

RESPIRATORY RESEARCH | 2020年 / 21卷 / 01期

关键词：

COVID-19; Pulmonary fibrosis; HRCT;

D O I：

10.1186/s12931-020-01550-6

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

It has been recently hypothesized that infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may lead to fibrotic sequelae in patients recovering from coronavirus disease 2019 (COVID-19). In this observational study, hospitalized patients with COVID-19 had a HRCT of the chest performed to detect the extension of fibrotic abnormalities via Hounsfield Units (HU). At follow-up, the lung density significantly improved in both lungs and in each lobe of all patients, being in the normal range (- 950 to - 700 HU). This study provides preliminary evidence that hospitalized patients with mild-to-moderate forms of COVID-19 are not at risk of developing pulmonary fibrosis.

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