Langerhans cell sarcoma

被引：42

作者：

Ferringer, Tammie

Banks, Peter M.

Metcalf, John S.

机构：

[1] Med Univ S Carolina, Charleston, SC 29425 USA

[2] Carolinas Med Ctr, Dept Pathol, Charlotte, NC 28203 USA

来源：

AMERICAN JOURNAL OF DERMATOPATHOLOGY | 2006年 / 28卷 / 01期

关键词：

Langerhans cell; Langerhans cell sarcoma; histiocytosis; dendritic cells;

D O I：

10.1097/01.dad.0000146314.52378.c2

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Proliferations of Langerhans cells can be histologically divided into cytologically benign Langerhans cell proliferations, which include the clinical syndromes of Langerhans cell histiocytosis, and cytologically malignant Langerhans cell sarcoma. We report a Langerhans cell sarcoma in a 33-year-old male that arose on the posterior thigh with subsequent regional lymph node involvement. Conventional microscopic, immunohistochemical, and, ultrastructural analysis confirmed Langerhans cell differentiation. Aberrant CD31 expression, similar to that described previously in Langerhans cell histiocytosis, was prominent in this tumor, possibly enhancing its migratory capabilities.

引用

页码：36 / 39

页数：4

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