Heterozygosity at the TPMT gene locus, augmented by mutated MTHFR gene, predisposes to 6-MP related toxicities in childhood ALL patients

被引：42

作者：

Karas-Kuzelicki, N. ^{[1
]}

Jazbec, J. ^{[2
]}

Milek, M. ^{[1
]}

Mlinaric-Rascan, I. ^{[1
]}

机构：

[1] Univ Ljubljana, Fac Pharm, Dept Clin Biochem, Ljubljana, Slovenia

[2] Univ Med Ctr, Univ Childrens Hosp, Unit Oncol & Hematol, Ljubljana, Slovenia

来源：

LEUKEMIA | 2009年 / 23卷 / 05期

关键词：

METHYLTRANSFERASE; PHARMACOGENETICS;

D O I：

10.1038/leu.2008.317

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

[No abstract available]

引用

页码：971 / 974

页数：4

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[5]

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