Scleral and corneal xanthomatous inflammation in a gray mouse lemur (Microcebus murinus)

被引:6
作者
Alleaume, Charline [1 ]
El Mrini, Meryem [1 ]
Laloy, Eve [1 ]
Marchal, Julia [2 ]
Aujard, Fabienne [2 ]
Chahory, Sabine [3 ]
机构
[1] Univ Paris Est, Ecole Natl Vet Alfort, Unite Histol Embryol & Anat Pathol, F-94704 Maisons Alfort, France
[2] Museum Natl Hist Nat, CNRS, Mecanismes Adaptatifs & Evolut, F-91800 Brunoy, France
[3] Univ Paris Est, Ecole Natl Vet Alfort, UP Ophtalmol, F-94704 Maisons Alfort, France
关键词
cornea; gray mouse lemur; Microcebus murinus; sclera; xanthomatous inflammation; CHOLESTEROL GRANULOMAS; LIPID KERATOPATHY; DOG; HYPERLIPIDEMIA; PRIMATE;
D O I
10.1111/vop.12374
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Bilateral multifocal corneal opacity was detected in a 4.5-year-old male captive gray mouse lemur (Microcebus murinus) without other clinical ocular changes. Histopathological examination revealed a severe diffuse granulomatous scleritis and focal keratitis with intralesional cholesterol, consistent with xanthomatous inflammation. This is the first report of xanthomatous inflammation in a gray mouse lemur. This condition may be the result of systemic factors (lipid metabolism disorders) and/or local predisposing factors such as hemorrhage or inflammation. The pathogenesis in this case could not be fully determined. Further studies on lemurs are required for a better understanding of their lipid metabolism, as well as for diagnosing and evaluating the incidence of xanthomatous inflammation in these species.
引用
收藏
页码:177 / 180
页数:4
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