Endocrine Disorders in Thalassemia Major Patients: A Review

被引：0
作者：
Hamidi, Zohreh [1 ]
机构：
[1] Univ Tehran Med Sci, Endocrinol & Metab Clin Sci Inst, Endocrinol & Metab Res Ctr, Tehran, Iran
来源：
KUWAIT MEDICAL JOURNAL | 2016年 / 48卷 / 01期
关键词：
hypogonadism; hypopituitarism; GH deficiency; iron overload; osteoporosis; BETA-THALASSEMIA; HYPOPARATHYROIDISM; COMPLICATIONS; OSTEOPOROSIS; TRANSFUSION; ADOLESCENTS; SECRETION; DENSITY; DISEASE; IRON;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Recently, due to increased thalassemia major (TM) patients' life expectancy, the issue of endocrine disorders in children, adolescents and young adults with TM has attracted much attention as a prominent cause of morbidity despite adequate transfusion and iron chelation therapy. Frequency of one endocrinopathy, two simultaneous endocrinopathy, and patients with three endocrine disorders, reported 40.0%, 26.7% and 6.7%, respectively. The main risk factor of endocrine disorders is iron overload due to multi transfusion. An overview of thalassemia major, effects of iron overload on endocrine system as a whole and one by one are included in this review. Also some points about management of endocrinopathies in these patients, mentioned at the end.
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页码：4 / 11
页数：8
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