Computer-aided sperm analysis: past, present and future

被引:96
作者
Lu, J. C. [1 ]
Huang, Y. F. [2 ]
Lu, N. Q. [3 ]
机构
[1] PLA, Nanjing Hosp, Dept Lab Sci, Jiangsu Corps,Armed Police Force, Nanjing 210028, Jiangsu, Peoples R China
[2] Jinling Hosp, Inst Clin Lab Med, Nanjing, Jiangsu, Peoples R China
[3] Jiangsu Family Planning Res Inst, Nanjing 210036, Jiangsu, Peoples R China
关键词
Clinical application; computer-aided sperm analysis; influencing factor; quality control; standardisation; SEMEN ANALYSIS CASA; HUMAN SPERMATOZOA; IN-VITRO; MOTILITY CHARACTERISTICS; QUALITY ANALYZER; STRICT CRITERIA; INFERTILE MEN; CHAMBER DEPTH; FERTILIZATION; PARAMETERS;
D O I
10.1111/and.12093
中图分类号
R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
摘要
Computer-aided sperm analysis (CASA) system has been accepted and used commonly as a routine semen analysis instrument in hospital clinical laboratories worldwide. However, technicians in clinical laboratories have little informed knowledge about the principles of CASA system and the sources of analysis errors. In this review, we focus on the concept of CASA, the development course of CASA technology, the clinical application of CASA systems and the factors influencing the accuracies of results, such as frame rate, sperm counting chambers affiliated to the CASA system, algorithms and sperm concentration. These factors and lack of internal quality control may result in huge errors of the CASA between systems and laboratories. It is therefore necessary to perform the standardisation and quality control for CASA.
引用
收藏
页码:329 / 338
页数:10
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