Synthesis of 7-epi-Goniodiol by Proline-Catalyzed Diastereoselective Direct Aldol Reaction

被引：6
|
作者：
Veena, Bacchu [1 ]
Sharma, Gangavaram V. M. [1 ]
机构：
[1] Indian Inst Chem Technol, CSIR, Discovery Lab, Organ & Biomol Chem Div, Hyderabad 500007, Andhra Pradesh, India
来源：
SYNLETT | 2014年 / 25卷 / 09期
关键词：
styryllactones; 7-epi-goniodiol; proline; aldol reaction; Baeyer-Villiger oxidation; GONIOTHALAMIN; LACTONES;
D O I：
10.1055/s-0033-1341107
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple organocatalytic approach was developed for the total synthesis of 7-epi-goniodiol. The strategy involves l-proline-catalyzed diastereoselective direct aldol reaction and Baeyer-Villiger oxidation as key steps for the construction of chiral lactone.
引用
收藏
页码：1283 / 1286
页数：4
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