Cathepsin G is broadly expressed in acute myeloid leukemia and is an effective immunotherapeutic target

被引：22

作者：

Alatrash, G. ^{[1
]}

Garber, H. R. ^{[1
]}

Zhang, M. ^{[1
]}

Sukhumalchandra, P. ^{[1
]}

Qiu, Y. ^{[2
]}

Jakher, H. ^{[1
]}

Perakis, A. A. ^{[1
]}

Becker, L. ^{[1
]}

Yoo, S. Y. ^{[3
]}

Dwyer, K. C. ^{[1
]}

Coombes, K. ^{[4
]}

Talukder, A. H. ^{[5
]}

St John, L. S. ^{[1
]}

Senyukov, V. ^{[6
]}

Lee, D. A. ^{[6
]}

Sergeeva, A. ^{[1
]}

He, H. ^{[1
]}

Ma, Q. ^{[1
]}

Armistead, P. M. ^{[7
]}

Roszik, J. ^{[5
,8
]}

Mittendorf, E. A. ^{[9
]}

Molldrem, J. J. ^{[1
]}

Hawke, D. ^{[10
]}

Lizee, G.

Kornblau, S. M. ^{[2
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Dept Stem Cell Transplantat & Cellular Therapy, Sect Transplant Immunol, Houston, TX 77030 USA

[2] MD Anderson Canc Ctr, Dept Leukemia, Houston, TX USA

[3] MD Anderson Canc Ctr, Dept Bioinformat & Computat Biol, Houston, TX USA

[4] Ohio State Univ, Dept Biomed Informat, Columbus, OH 43210 USA

[5] MD Anderson Canc Ctr, Dept Melanoma Med Oncol, Houston, TX USA

[6] MD Anderson Canc Ctr, Dept Pediat, Houston, TX USA

[7] Univ N Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC USA

[8] MD Anderson Canc Ctr, Dept Genom Med, Houston, TX USA

[9] MD Anderson Canc Ctr, Dept Surg Oncol, Houston, TX USA

[10] MD Anderson Canc Ctr, Dept Syst Biol, Houston, TX USA

来源：

LEUKEMIA | 2017年 / 31卷 / 01期

基金：

美国国家卫生研究院;

关键词：

HIPPO PATHWAY; AML; MUTATIONS; CELLS;

D O I：

10.1038/leu.2016.249

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：234 / 237

页数：4

共 15 条

[1] Molecular mutations are prognostically relevant in AML with intermediate risk cytogenetics and aberrant karyotype
Bacher, U.
Haferlach, T.
Alpermann, T.
Kern, W.
Schnittger, S.
Haferlach, C.
[J]. LEUKEMIA, 2013, 27 (02) : 496 - 500
[2] Expression of ARC (apoptosis repressor with caspase recruitment domain), an antiapoptotic protein, is strongly prognostic in AML
Carter, Bing Z.
Qiu, Yi Hua
Zhang, Nianxiang
Coombes, Kevin R.
Mak, Duncan H.
Thomas, Deborah A.
Ravandi, Farhad
Kantarjian, Hagop M.
Koller, Erich
Andreeff, Michael
Kornblau, Steven M.
[J]. BLOOD, 2011, 117 (03) : 780 - 787
[3] Hematopoietic stem cell transplantation for patients with AML in first complete remission
Cornelissen, Jan J.
Blaise, Didier
[J]. BLOOD, 2016, 127 (01) : 62 - 70
[4] An update of current treatments for adult acute myeloid leukemia
Dombret, Herve
Gardin, Claude
[J]. BLOOD, 2016, 127 (01) : 53 - 61
[5] In vitro induction of myeloid leukemia-specific CD4 and CD8 T cells by CD40 ligand-activated B cells gene modified to express primary granule proteins
Fujiwara, H
Melenhorst, JJ
El Ouriaghli, F
Kajigaya, S
Grube, M
Sconocchia, G
Rezvani, K
Price, DA
Hensel, NF
Douek, DC
Barrett, AJ
[J]. CLINICAL CANCER RESEARCH, 2005, 11 (12) : 4495 - 4503
[6] Garwicz D, 2005, HAEMATOLOGICA, V90, P38
[7] Surface plasmon resonance imaging biosensor for cathepsin G based on a potent inhibitor: Development and applications
Gorodkiewicz, Ewa
Sienczyk, Marcin
Regulska, Elzbieta
Grzywa, Renata
Pietrusewicz, Ewa
Lesner, Adam
Lukaszewski, Zenon
[J]. ANALYTICAL BIOCHEMISTRY, 2012, 423 (02) : 218 - 223
[8] Very low frequencies of human normal CD34+ haematopoietic progenitor cells express the Wilms' tumour gene WT1 at levels similar to those in leukaemia cells
Hosen, N
Sonoda, Y
Oji, Y
Kimura, T
Minamiguchi, H
Tamaki, H
Kawakami, M
Asada, M
Kanato, K
Motomura, M
Murakami, M
Fujioka, T
Masuda, T
Kim, EH
Tsuboi, A
Oka, Y
Soma, T
Ogawa, H
Sugiyama, H
[J]. BRITISH JOURNAL OF HAEMATOLOGY, 2002, 116 (02) : 409 - 420
[9] Identification of a fusion gene composed of a Hippo pathway gene MST2 and a common translocation partner ETV6 in a recurrent translocation t(8;12)(q22;p13) in acute myeloid leukemia
Ogawa, Shinichi
Yokoyama, Yasuhisa
Suzukawa, Kazumi
Nanmoku, Toru
Kurita, Naoki
Seki, Masanori
Maie, Koichiro
Suyama, Takuya
Takaiwa, Naoko
Sakata-Yanagimoto, Mamiko
Obara, Naoshi
Hasegawa, Yuichi
Chiba, Shigeru
[J]. ANNALS OF HEMATOLOGY, 2015, 94 (08) : 1431 - 1433
[10] Activity of 8F4, a T-cell receptor-like anti-PR1/HLA-A2 antibody, against primary human AML in vivo
Sergeeva, A.
He, H.
Ruisaard, K.
St John, L.
Alatrash, G.
Clise-Dwyer, K.
Li, D.
Patenia, R.
Hong, R.
Sukhumalchandra, P.
You, M. J.
Gagea, M.
Ma, Q.
Molldrem, J. J.
[J]. LEUKEMIA, 2016, 30 (07) : 1475 - 1484

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