Human recombinant soluble ACE2 in severe COVID-19

被引：309

作者：

Zoufaly, Alexander ^{[1
]}

Poglitsch, Marko ^{[3
]}

Aberle, Judith H. ^{[4
]}

Hoepler, Wolfgang ^{[1
]}

Seitz, Tamara ^{[1
]}

Traugott, Marianna ^{[1
]}

Grieb, Alexander ^{[1
]}

Pawelka, Erich ^{[1
]}

Laferl, Hermann ^{[1
]}

Wenisch, Christoph ^{[1
]}

Neuhold, Stephanie ^{[1
]}

Haider, Doris ^{[2
]}

Stiasny, Karin ^{[4
]}

Bergthaler, Andreas ^{[5
]}

Puchhammer-Stoeckl, Elisabeth ^{[4
]}

Mirazimi, Ali ^{[6
]}

Montserrat, Nuria ^{[7
]}

Zhang, Haibo ^{[8
]}

Slutsky, Arthur S. ^{[8
]}

Penninger, Josef M. ^{[9
,10
]}

机构：

[1] Kaiser Franz Josef Hosp, Dept Med 4, Clin Favoriten, A-1100 Vienna, Austria

[2] Kaiser Franz Josef Hosp Clin Favoriten, Dept Pharm, Vienna, Austria

[3] Attoquant Diagnost GmbH, Vienna, Austria

[4] Med Univ Vienna, Ctr Virol, Vienna, Austria

[5] Austrian Acad Sci, CeMM Res Ctr Mol Med, Vienna, Austria

[6] Karolinska Inst, Dept Lab Med, Stockholm, Sweden

[7] Barcelona Inst Sci & Technol Technol BIST, Catalan Inst Res & Adv Studies ICREA, Inst Bioengn Catalonia IBEC, Barcelona, Spain

[8] Univ Toronto, Unity Hlth Toronto, St Michaels Hosp, Keenan Res Ctr,Li Ka Shing Knowledge Inst, Toronto, ON, Canada

[9] Univ British Columbia, Dept Med Genet, Inst Life Sci, Vancouver, BC, Canada

[10] Austrian Acad Sci, Inst Mol Biotechnol, Vienna, Austria

来源：

LANCET RESPIRATORY MEDICINE | 2020年 / 8卷 / 11期

基金：

欧盟地平线“2020”;

关键词：

ANGIOTENSIN-CONVERTING ENZYME-2;

D O I：

10.1016/S2213-2600(20)30418-5

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

[No abstract available]

引用

页码：1154 / 1158

页数：5

共 24 条

[1] Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19
Ackermann, Maximilian
Verleden, Stijn E.
Kuehnel, Mark
Haverich, Axel
Welte, Tobias
Laenger, Florian
Vanstapel, Arno
Werlein, Christopher
Stark, Helge
Tzankov, Alexandar
Li, William W.
Li, Vincent W.
Mentzer, Steven J.
Jonigk, Danny
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 2020, 383 (02) : 120 - 128
[2] Angiotensin-converting enzyme 2 (ACE2),SARS-CoV-2 and the pathophysiology of coronavirus disease 2019 (COVID-19)
Bourgonje, Arno R.
Abdulle, Amaal E.
Timens, Wim
Hillebrands, Jan-Luuk
Navis, Gerjan J.
Gordijn, Sanne J.
Bolling, Marieke C.
Dijkstra, Gerard
Voors, Adriaan A.
Osterhaus, Albert D. M. E.
van Der Voort, Peter H. J.
Mulder, Douwe J.
van Goor, Harry
[J]. JOURNAL OF PATHOLOGY, 2020, 251 (03) : 228 - 248
[3] A strategic approach to COVID-19 vaccine R&D
Corey, Lawrence
Mascola, John R.
Fauci, Anthony S.
Collins, Francis S.
[J]. SCIENCE, 2020, 368 (6494) : 948 - 950
[4] Angiotensin-converting enzyme 2 is an essential regulator of heart function
Crackower, MA
Sarao, R
Oudit, GY
Yagil, C
Kozieradzki, I
Scanga, SE
Oliveira-dos-Santos, AJ
da Costa, J
Zhang, LY
Pei, Y
Scholey, J
Ferrario, CM
Manoukian, AS
Chappell, MC
Backx, PH
Yagil, Y
Penninger, JM
[J]. NATURE, 2002, 417 (6891) : 822 - 828
[5] Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System Celebrating the 20th Anniversary of the Discovery of ACE2
Gheblawi, Mahmoud
Wang, Kaiming
Viveiros, Anissa
Quynh Nguyen
Zhong, Jiu-Chang
Turner, Anthony J.
Raizada, Mohan K.
Grant, Maria B.
Oudit, Gavin Y.
[J]. CIRCULATION RESEARCH, 2020, 126 (10) : 1456 - 1474
[6] Angiotensin II induces interleukin-6 transcription in vascular smooth muscle cells through pleiotropic activation of nuclear factor-κB transcription factors
Han, YQ
Runge, MS
Brasier, AR
[J]. CIRCULATION RESEARCH, 1999, 84 (06) : 695 - 703
[7] Pharmacokinetics and Pharmacodynamics of Recombinant Human Angiotensin-Converting Enzyme 2 in Healthy Human Subjects
Haschke, Manuel
Schuster, Manfred
Poglitsch, Marko
Loibner, Hans
Salzberg, Marc
Bruggisser, Marcel
Penninger, Joseph
Kraehenbuehl, Stephan
[J]. CLINICAL PHARMACOKINETICS, 2013, 52 (09) : 783 - 792
[8] Angiotensin II plasma levels are linked to disease severity and predict fatal outcomes in H7N9-infected patients
Huang, Fengming
Guo, Jing
Zou, Zhen
Liu, Jun
Cao, Bin
Zhang, Shuyang
Li, Hui
Wang, Wei
Sheng, Miaomiao
Liu, Song
Pan, Jingcao
Bao, Changjun
Zeng, Mei
Xiao, Haixia
Qian, Guirong
Hu, Xinjun
Chen, Yuanting
Chen, Yu
Zhao, Yan
Liu, Qiang
Zhou, Huandi
Zhu, Jindong
Gao, Hainv
Yang, Shigui
Liu, Xiaoli
Zheng, Shufa
Yang, Jiezuan
Diao, Hongyan
Cao, Hongcui
Wu, Ying
Zhao, Min
Tan, Shuguang
Guo, Dan
Zhao, Xiliang
Ye, Yicong
Wu, Wei
Xu, Yingchun
Penninger, Josef M.
Li, Dangsheng
Gao, George F.
Jiang, Chengyu
Li, Lanjuan
[J]. NATURE COMMUNICATIONS, 2014, 5
[9] Angiotensin-converting enzyme 2 protects from severe acute lung failure
Imai, Y
Kuba, K
Rao, S
Huan, Y
Guo, F
Guan, B
Yang, P
Sarao, R
Wada, T
Leong-Poi, H
Crackower, MA
Fukamizu, A
Hui, CC
Hein, L
Uhlig, S
Slutsky, AS
Jiang, CY
Penninger, JM
[J]. NATURE, 2005, 436 (7047) : 112 - 116
[10] Plasma sRAGE is independently associated with increased mortality in ARDS: a meta-analysis of individual patient data
Jabaudon, Matthieu
Blondonnet, Raiko
Pereira, Bruno
Cartin-Ceba, Rodrigo
Lichtenstern, Christoph
Mauri, Tommaso
Determann, Rogier M.
Drabek, Tomas
Hubmayr, Rolf D.
Gajic, Ognjen
Uhle, Florian
Coppadoro, Andrea
Pesenti, Antonio
Schultz, Marcus J.
Ranieri, Marco V.
Brodska, Helena
Mrozek, Segolene
Sapin, Vincent
Matthay, Michael A.
Constantin, Jean-Michel
Calfee, Carolyn S.
[J]. INTENSIVE CARE MEDICINE, 2018, 44 (09) : 1388 - 1399

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