Genetic architecture of plant stress resistance: multi-trait genome-wide association mapping

被引：112

作者：

Thoen, Manus P. M. ^{[1
,2
,3
]}

Olivas, Nelson H. Davila ^{[1
]}

Kloth, Karen J. ^{[1
,2
,3
]}

Coolen, Silvia ^{[4
]}

Huang, Ping-Ping ^{[5
]}

Aarts, Mark G. M. ^{[5
]}

Bac-Molenaar, Johanna A. ^{[2
,5
]}

Bakker, Jaap ^{[6
]}

Bouwmeester, Harro J. ^{[2
]}

Broekgaarden, Colette ^{[4
,7
]}

Bucher, Johan ^{[7
]}

Busscher-Lange, Jacqueline ^{[1
,2
,3
]}

Cheng, Xi ^{[2
]}

Fradin, Emilie F. ^{[2
]}

Jongsma, Maarten A. ^{[3
]}

Julkowska, Magdalena M. ^{[8
,9
]}

Keurentjes, Joost J. B. ^{[5
]}

Ligterink, Wilco ^{[2
]}

Pieterse, Corne M. J. ^{[4
]}

Ruyter-Spira, Carolien ^{[2
]}

Smant, Geert ^{[6
]}

Testerink, Christa ^{[8
,9
]}

Usadel, Bjoern ^{[10
]}

van Loon, Joop J. A. ^{[1
]}

van Pelt, Johan A. ^{[4
]}

van Schaik, Casper C. ^{[6
]}

van Wees, Saskia C. M. ^{[4
]}

Visser, Richard G. F. ^{[7
]}

Voorrips, Roeland ^{[7
]}

Vosman, Ben ^{[7
]}

Vreugdenhil, Dick ^{[2
]}

Warmerdam, Sonja ^{[6
]}

Wiegers, Gerrie L. ^{[1
,3
]}

van Heerwaarden, Joost ^{[11
]}

Kruijer, Willem ^{[11
]}

van Eeuwijk, Fred A. ^{[11
]}

Dicke, Marcel ^{[1
]}

机构：

[1] Wageningen Univ & Res, Entomol Lab, POB 16, NL-6700 AA Wageningen, Netherlands

[2] Wageningen Univ & Res, Lab Plant Physiol, POB 16, NL-6700 AA Wageningen, Netherlands

[3] Wageningen Univ & Res, Business Unit Biosci, Wageningen Plant Res, POB 16, NL-6700 AA Wageningen, Netherlands

[4] Univ Utrecht, Plant Microbe Interact, Dept Biol, POB 800-56, NL-3508 TB Utrecht, Netherlands

[5] Wageningen Univ & Res, Genet Lab, POB 16, NL-6700 AA Wageningen, Netherlands

[6] Wageningen Univ & Res, Nematol Lab, POB 8213, NL-6700 ES Wageningen, Netherlands

[7] Wageningen Univ & Res, Wageningen Univ & Res Plant Breeding, POB 386, NL-6700 AJ Wageningen, Netherlands

[8] Univ Amsterdam, Sect Plant Physiol, Swammerdam Inst Life Sci, POB 94215, NL-1090 GE Amsterdam, Netherlands

[9] Univ Amsterdam, Sect Plant Cell Biol, Swammerdam Inst Life Sci, POB 94215, NL-1090 GE Amsterdam, Netherlands

[10] Rhein Westfal TH Aachen, Inst Biol 1, Worringer Weg 3, D-52074 Aachen, Germany

[11] Wageningen Univ & Res, Biometris, POB 16, NL-6700 AA Wageningen, Netherlands

来源：

NEW PHYTOLOGIST | 2017年 / 213卷 / 03期

关键词：

abiotic stress; biotic stress; genetic architecture; genome-wide association mapping; multiple stresses; DEPENDENT ANION CHANNEL; CINNAMOYL-COA REDUCTASE; ARABIDOPSIS-THALIANA; TRANSCRIPTION FACTORS; MIXED-MODEL; ABSCISIC-ACID; BIOTIC STRESS; DISEASE RESISTANCE; CORRELATED TRAITS; SALT;

D O I：

10.1111/nph.14220

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Plants are exposed to combinations of various biotic and abiotic stresses, but stress responses are usually investigated for single stresses only. Here, we investigated the genetic architecture underlying plant responses to 11 single stresses and several of their combinations by phenotyping 350 Arabidopsis thaliana accessions. A set of 214 000 single nucleotide polymorphisms (SNPs) was screened for marker-trait associations in genome-wide association (GWA) analyses using tailored multi-trait mixed models. Stress responses that share phytohormonal signaling pathways also share genetic architecture underlying these responses. After removing the effects of general robustness, for the 30 most significant SNPs, average quantitative trait locus (QTL) effect sizes were larger for dual stresses than for single stresses. Plants appear to deploy broad-spectrum defensive mechanisms influencing multiple traits in response to combined stresses. Association analyses identified QTLs with contrasting and with similar responses to biotic vs abiotic stresses, and below-ground vs above-ground stresses. Our approach allowed for an unprecedented comprehensive genetic analysis of how plants deal with a wide spectrum of stress conditions.

引用

页码：1346 / 1362

页数：17

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