Representation matters: a call for inclusivity and equity in heart failure clinical trials

被引：5
|
作者：
Reza, Nosheen [1 ]
Nayak, Aditi [2 ]
Lewsey, Sabra C. [3 ]
DeFilippis, Ersilia M. [4 ]
机构：
[1] Univ Penn, Dept Med, Div Cardiovasc Med, Perelman Sch Med, 11 South Tower,Room 11-145,3400 Civ Ctr Blvd, Philadelphia, PA 19104 USA
[2] Emory Univ, Div Cardiol, Atlanta, GA 30322 USA
[3] Johns Hopkins Univ, Dept Med, Div Cardiol, Sch Med, Baltimore, MD 21211 USA
[4] Columbia Univ, Dept Med, Div Cardiol, Coll Phys & Surg New York, New York, NY 10027 USA
来源：
EUROPEAN HEART JOURNAL SUPPLEMENTS | 2022年 / 24卷
关键词：
Diversity; Health equity; Clinical trials; Heart failure; DISPARITIES; FUTURE;
D O I：
10.1093/eurheartjsupp/suac115
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The burden of heart failure remains substantial worldwide, and heart failure with reduced ejection fraction (HFrEF) affects approximately half of this population. Despite this global prevalence of HFrEF, the majority of contemporary clinical trials in HFrEF have underenrolled individuals from minoritized sex, gender, race, ethnicity, and socioeconomic groups. Moreover, significant disparities in access to HFrEF treatment and outcomes exist across these same strata. We provide a call to action for the inclusion of diverse populations in HFrEF clinical trials; catalogue several barriers to adequate representation in HFrEF clinical trials; and propose strategies to broaden inclusivity in future HFrEF trials.
引用
收藏
页码：L45 / L48
页数：4
相关论文
共 50 条
  • [1] Representation of Black patients in heart failure clinical trials
    Azam, Tariq U.
    Colvin, Monica M.
    CURRENT OPINION IN CARDIOLOGY, 2021, 36 (03) : 329 - 334
  • [2] Representation of the elderly, women, and minorities in heart failure clinical trials
    Heiat, A
    Gross, CP
    Krumholz, HM
    ARCHIVES OF INTERNAL MEDICINE, 2002, 162 (15) : 1682 - 1688
  • [3] Representation of Women Authors in Contemporary Heart Failure Clinical Trials
    Ho, Annie H.
    Tahhan, Ayman Samman
    Vaduganathan, Muthiah
    Greene, Stephen J.
    Alrohaibani, Alaaeddin
    Fonarow, Gregg C.
    Butler, Javed
    O'Connor, Christopher
    Fiuzat, Mona
    Pina, Ileana L.
    Lindenfeld, JoAnn
    Jessup, Mariell
    CIRCULATION, 2019, 140
  • [4] Representation Matters-Diversity in Retina Clinical Trials
    Baxter, Sally L.
    JAMA OPHTHALMOLOGY, 2022, 140 (11) : 1103 - 1104
  • [5] Enrollment Matters: The Reality of Disparity and Pursuit of Equity in Clinical Trials
    Winn, Robert A.
    CANCER DISCOVERY, 2022, 12 (06) : 1419 - 1422
  • [6] Clinical trials in heart failure
    Hobbs, R
    ADVANCES IN HEART FAILURE, 2002, : 351 - 356
  • [7] Clinical trials on heart failure
    Aguilar, JC
    Martínez, AH
    REVISTA ESPANOLA DE CARDIOLOGIA, 2001, 54 : 22 - 31
  • [8] REPRESENTATION OF WOMEN AND RACIAL MINORITIES IN HEART FAILURE CLINICAL TRIALS: A SYSTEMATIC REVIEW
    Umeh, Chukwuemeka
    Gupta, Rahul
    Kaur, Gagan
    Raghav, Dhawan
    Darji, Puja
    Eghreriniovo, Benson
    Mohta, Tamanna Vinodkumar
    Kumar, Sabina
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2024, 83 (13) : 589 - 589
  • [9] Representation of Women Authors in International Heart Failure Guidelines and Contemporary Clinical Trials
    Reza, Nosheen
    Tahhan, Ayman Samman
    Mahmud, Nadim
    DeFilippis, Ersilia M.
    Alrohaibani, Alaaeddin
    Vaduganathan, Muthiah
    Greene, Stephen J.
    Ho, Annie Hang
    Fonarow, Gregg C.
    Butler, Javed
    O'Connor, Christopher
    Fiuzat, Mona
    Vardeny, Orly
    Pina, Ileana L.
    Lindenfeld, JoAnn
    Jessup, Mariell
    CIRCULATION-HEART FAILURE, 2020, 13 (08) : E006605
  • [10] Conduct of Clinical Trials in Acute Heart Failure: Regional Differences in Heart Failure Clinical Trials
    Fiuzat, Mona
    Califf, Robert M.
    HEART FAILURE CLINICS, 2011, 7 (04) : 539 - +
12345