Lactones from Angiopteris caudatiformis

被引：29

作者：

Yu, Yong-Ming ^{[1
]}

Yang, Jun-Shan ^{[1
]}

Peng, Chao-Zhong ^{[1
]}

Caer, Valerie ^{[3
]}

Cong, Pu-Zhu ^{[1
]}

Zou, Zhong-Mei ^{[1
]}

Lu, Yang ^{[2
]}

Yang, Shi-Ying ^{[2
]}

Gu, Yu-Cheng ^{[1
,3
]}

机构：

[1] Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100193, Peoples R China

[2] Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China

[3] Syngenta Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England

来源：

JOURNAL OF NATURAL PRODUCTS | 2009年 / 72卷 / 05期

关键词：

EUREMA-HECABE-MANDARINA; OSMUNDA-JAPONICA; FERN GLYCOSIDE; ANTIFEEDANTS; INSECTS; LARVAE;

D O I：

10.1021/np900027m

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Angiopterlactones A (1) and B (2), two unique lactones, and three known lactones, osmundalactone (3), osmundalin (4), and 3,5-dihydroxy-gamma-caprolactone (5), have been isolated from the rhizome of Angiopteris caudatiformis. The structures of I and 2 were determined by NMR and MS methods, and the structure of 2 was confirmed by X-ray crystallography. The absolute configurations of I and 2 were assigned by application of the CD excitation chirality method and the modified Mosher's method. Compound 1 was slightly cytotoxic against HeLa cells, with an IC50 value of 68.8 mu M, and compounds 3 and 4 showed moderate insect antifeeding activity against Plutella xylostella and Heliothis virescens.

引用

页码：921 / 924

页数：4

共 13 条

[1]

BEECHAM AF, 1968, TETRAHEDRON LETT, P3591

[2]

FANG ZX, 2006, TU JIA ZU YAO WU ZHI, P507

[3] ISOLATION AND STRUCTURE DETERMINATION OF FERN GLYCOSIDE OSMUNDALIN AND SYNTHESIS OF ITS AGLYCONE OSMUNDALACTONE [J].

HOLLENBEAK, KH ;

KUEHNE, ME .

TETRAHEDRON, 1974, 30 (15) :2307-2316

[4] STRUCTURE OF ANGIOPTEROSIDE (4-0-BETA-D-GLUCOPYRANOSYL-L-THREO-2-HEXEN-5-OLIDE) MONOHYDRATE, A FERN GLYCOSIDE FROM ANGIOPTERIS-LYGODIIFOLIA ROS [J].

HSEU, TH .

ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE, 1981, 37 (NOV) :2095-2098

[5] Screening for antifeedant and larvicidal activity of plant extracts against Helicoverpa armigera (Hubner), Sylepta derogata (F.) and Anopheles stephensi (Liston) [J].

Kamaraj, C. ;

Rahuman, A. Abdul ;

Bagavan, A. .

PARASITOLOGY RESEARCH, 2008, 103 (06) :1361-1368

[6]

MISONG J, 2008, J NAT PRODUCTS, V71, P1714

[7]

NUMATA A, 1984, CHEM PHARM BULL, V32, P2815

[8] PLANT CONSTITUENTS BIOLOGICALLY-ACTIVE TO INSECTS .6. ANTIFEEDANTS FOR LARVAE OF THE YELLOW BUTTERFLY, EUREMA-HECABE-MANDARINA, IN OSMUNDA-JAPONICA [J].

NUMATA, A ;

TAKAHASHI, C ;

FUJIKI, R ;

KITANO, E ;

KITAJIMA, A ;

TAKEMURA, T .

CHEMICAL & PHARMACEUTICAL BULLETIN, 1990, 38 (10) :2862-2865

[9]

OLLIS WD, 1979, TETRAHEDRON, V35, P105

[10]

Riham S. E. D., 2008, CHEM PHARM BULL, V56, P642

← 1 2 →