Human chorionic gonadotropin inhibits insulin-like growth factor-binding protein-1 and prolactin in decidualized human endometrial stromal cells

被引:36
作者
Fluhr, Herbert [1 ]
Krenzer, Stefanie [1 ]
Deperschmidt, Margarita [1 ]
Zwirner, Manfred [1 ]
Wallwiener, Diethelm [1 ]
Licht, Peter [1 ]
机构
[1] Univ Tubingen, Dept Obstet & Gynecol, Div Gynecol Endocrinol & Reprod Med, Tubingen, Germany
关键词
INTRAUTERINE MICRODIALYSIS; TROPHOBLAST INTERFACE; EARLY-PREGNANCY; MESSENGER-RNA; IMPLANTATION; EXPRESSION; BABOON;
D O I
10.1016/j.fertnstert.2005.12.031
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Recent data clearly show that hCG, as one of the first hormonal signals of the embryo, is involved in the modulation of endometrial receptivity in the secretory phase. Here we report a significant dose- and time-dependent inhibition of insulin-like growth factor-binding protein-1 and prolactin by hCG in human endometrial stromal cells after decidualization in vitro-findings that further underline the role of hCG in the endometrial milieu during early implantation.
引用
收藏
页码:236 / 238
页数:3
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