CRNDE: An important oncogenic long non-coding RNA in human cancers

被引：65
|
作者：
Zhang, Jiaming [1 ,2 ]
Yin, Minuo [3 ]
Peng, Gang [1 ]
Zhao, Yingchao [1 ]
机构：
[1] Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Ctr Canc, Wuhan, Hubei, Peoples R China
[2] Huazhong Univ Sci & Technol, Tongji Hosp, Dept Orthoped, Tongji Med Coll, Wuhan, Hubei, Peoples R China
[3] Huazhong Univ Sci & Technol, Union Hosp, Dept Obstet & Gynecol, Tongji Med Coll, Wuhan, Hubei, Peoples R China
来源：
CELL PROLIFERATION | 2018年 / 51卷 / 03期
基金：
中国国家自然科学基金;
关键词：
CRNDE; human cancer; lncRNA; prognosis; PROMOTES CELL-PROLIFERATION; COMPETING ENDOGENOUS RNA; EXPRESSION PROFILES; COLORECTAL-CANCER; SIGNALING PATHWAY; POOR-PROGNOSIS; GLIOMA; LNCRNA; GROWTH; PROGRESSION;
D O I：
10.1111/cpr.12440
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Aberrant overexpression of long non-coding RNA CRNDE (Colorectal Neoplasia Differentially Expressed) is confirmed in various human cancers, which is correlated with advanced clinicopathological features and poor prognosis. CRNDE promotes cancer cell proliferation, migration and invasion, and suppresses apoptosis in complicated mechanisms, which result in the initialization and development of human cancers. In this review, we provide an overview of the oncogenic role and potential clinical applications of CRNDE.
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页数：6
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