Serum VEGF levels in gastric cancer patients: correlation with clinicopathological parameters

被引：15
|
作者：
Bilgic, Celal Ismail [1 ]
Tez, Mesut [1 ]
机构：
[1] Ankara Numune Training & Res Hosp, Dept Gen Surg, Ankara, Turkey
来源：
TURKISH JOURNAL OF MEDICAL SCIENCES | 2015年 / 45卷 / 01期
关键词：
Gastric cancer; vascular endothelial growth factor; angiogenesis; ENDOTHELIAL GROWTH-FACTOR; CARCINOEMBRYONIC ANTIGEN; PROGNOSTIC-SIGNIFICANCE; FACTOR EXPRESSION; INTERLEUKIN-6; ANGIOGENESIS; BFGF;
D O I：
10.3906/sag-1401-154
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Background/aim: To evaluate the predictive role of the circulating levels of vascular endothelial growth factor (VEGF) in gastric cancer patients. Materials and methods: This study is a case-control study. We measured serum VEGF levels of 30 patients aged between 34 and 83 years with gastric cancer and 30 patients without malignant pathology, operated on for benign pathologies, with ages ranging from 18 to 69. Results: Serum levels of VEGF were correlated with the tumor type classification (signet cell adenocarcinoma) and the presence of adjacent tissue invasion. There was also a positive correlation between serum VEGF and carcinoembryonic antigen levels. Conclusion: In gastric cancer patients, serum VEGF levels may provide additional prognostic information for preoperative evaluation of invasion and tumor type.
引用
收藏
页码：112 / 117
页数：6
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