Synthesis, properties and biomedical applications of hydrolytically degradable materials based on aliphatic polyesters and polycarbonates

被引：280

作者：

Brannigan, Ruairi P. ^{[1
]}

Dove, Andrew P. ^{[1
]}

机构：

[1] Univ Warwick, Dept Chem, Coventry CV4 7AL, W Midlands, England

来源：

BIOMATERIALS SCIENCE | 2017年 / 5卷 / 01期

关键词：

RING-OPENING POLYMERIZATION; IN-VITRO DEGRADATION; BIODEGRADABLE POLYMERS; TRIMETHYLENE CARBONATE; POLY(TRIMETHYLENE CARBONATE); THERMOPLASTIC ELASTOMERS; MECHANICAL-PROPERTIES; TRIBLOCK COPOLYMERS; MOLECULAR-WEIGHT; L-LACTIDE;

D O I：

10.1039/c6bm00584e

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

Polyester-based polymers represent excellent candidates in synthetic biodegradable and bioabsorbable materials for medical applications owing to their tailorable properties. The use of synthetic polyesters as biomaterials offers a unique control of morphology, mechanical properties and degradation profile through monomer selection, polymer composition (i.e. copolymer vs. homopolymer, stereocomplexation etc.) and molecular weight. Within this review, the synthetic routes, degradation modes and application of aliphatic polyester-and polycarbonate-based biomaterials are discussed.

引用

页码：9 / 21

页数：13

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