2015 Recommendations for the Management of Polymyalgia Rheumatica A European League Against Rheumatism/American College of Rheumatology Collaborative Initiative

被引：73

作者：

Dejaco, Christian ^{[1
,2
]}

Singh, Yogesh P. ^{[2
]}

Perel, Pablo ^{[3
]}

Hutchings, Andrew ^{[4
]}

Camellino, Dario ^{[5
,6
]}

Mackie, Sarah ^{[7
,8
]}

Abril, Andy ^{[9
]}

Bachta, Artur ^{[10
]}

Balint, Peter ^{[11
]}

Barraclough, Kevin

Bianconi, Lina

Buttgereit, Frank ^{[12
]}

Carsons, Steven ^{[13
]}

Ching, Daniel ^{[14
]}

Cid, Maria ^{[15
]}

Cimmino, Marco

Diamantopoulos, Andreas ^{[16
]}

Docken, William ^{[17
]}

Duftner, Christina ^{[18
]}

Fashanu, Billy ^{[2
]}

Gilbert, Kate ^{[19
]}

Hildreth, Pamela ^{[19
]}

Hollywood, Jane ^{[2
]}

Jayne, David ^{[20
]}

Lima, Manuella ^{[21
]}

Maharaj, Ajesh ^{[22
]}

Mallen, Christian ^{[23
]}

Martinez-Taboada, Victor ^{[24
]}

Maz, Mehrdad ^{[25
]}

Merry, Steven ^{[26
]}

Miller, Jean ^{[19
]}

Mori, Shunsuke ^{[27
]}

Neill, Lorna ^{[19
]}

Nordborg, Elisabeth ^{[28
]}

Nott, Jennifer ^{[19
]}

Padbury, Hannah ^{[19
]}

Pease, Colin

Salvarani, Carlo ^{[29
]}

Schirmer, Michael

Schmidt, Wolfgang ^{[30
]}

Spiera, Robert ^{[31
]}

Tronnier, David ^{[32
]}

Wagner, Alexandre ^{[33
]}

Whitlock, Madeline ^{[2
]}

Matteson, Eric L. ^{[34
]}

Dasgupta, Bhaskar ^{[2
]}

机构：

[1] Med Univ Graz, Dept Rheumatol, Graz, Austria

[2] Southend Univ Hosp, Dept Rheumatol, Westcliff On Sea SS0 0RY, Essex, England

[3] London Sch Hyg & Trop Med, Epidemiol & Populat Hlth Fac, London WC1, England

[4] London Sch Hyg & Trop Med, Dept Hlth Serv Res & Policy, London WC1, England

[5] Univ Genoa, Dept Internal Med, Res Lab, I-16126 Genoa, Italy

[6] Acad Div Clin Rheumatol, Genoa, Italy

[7] Univ Leeds, NIHR Leeds Musculoskeletal Biomed Res Unit, Leeds, W Yorkshire, England

[8] Leeds Inst Rheumat & Musculoskeletal Med, Leeds, W Yorkshire, England

[9] Mayo Clin, Dept Rheumatol, Jacksonville, FL 32224 USA

[10] Mil Inst Med, Dept Internal Med & Rheumatol, Warsaw, Poland

[11] Natl Inst Rheumatism & Physiotherapy, Dept Rheumatol 3, Budapest, Hungary

[12] Charite, Dept Rheumatol, D-13353 Berlin, Germany

[13] SUNY Stony Brook, Sch Med, Div Rheumatol Allergy & Immunol, Mineola, NY USA

[14] Timaru Hosp, Dept Rheumatol, Timaru, New Zealand

[15] Univ Barcelona, Hosp Clin, Dept System Autoimmune Dis, Barcelona, Spain

[16] Hosp Southern Norway Trust, Dept Rheumatol, Kristiansand, Norway

[17] Brigham & Womens Hosp, Div Rheumatol, Boston, MA 02115 USA

[18] Med Univ Innsbruck, Dept Internal Med Clin 6, A-6020 Innsbruck, Austria

[19] Polymyalgia Rheumat & Giant Cell Arteritis UK, London, England

[20] Univ Cambridge, Dept Med, Cambridge CB2 2QQ, England

[21] Hosp Univ Pedro Ernesto, Rio De Janeiro, Brazil

[22] Univ KwaZulu Natal, Prince Mshiyeni Mem Hosp, Nelson R Mandela Sch Med, Dept Internal Med, Durban, South Africa

[23] Keele Univ, Arthrit Res UK Primary Care Ctr, Keele ST5 5BG, Staffs, England

[24] Univ Cantabria, Hosp Univ Marques Valdecilla, Fac Med, Serv Reumatol, E-39005 Santander, Spain

[25] Univ Kansas Med Ctr, Dept Med, Div Allergy Clin Immunol & Rheumatol, Kansas City, KS USA

[26] Mayo Clin, Dept Family Med, Rochester, MN USA

[27] Kumamoto Saishunsou Natl Hosp, Clin Res Ctr Rheumat Dis, Dept Rheumatol, Kumamoto, Japan

[28] Sahlgrens Univ Hosp, Dept Rheumatol, S-41345 Gothenburg, Sweden

[29] Azienda Osped IRCCS Reggio Emilia, Dept Internal Med, Div Rheumatol, Reggio Emilia, Italy

[30] Immanuel Krankenhaus Berlin & Med Ctr Rheumatol B, Berlin, Germany

[31] Hosp Special Surg, Dept Med, New York, NY 10021 USA

[32] Mayo Clin, Rochester, MN USA

[33] Univ Fed Sao Paulo, Dept Internal Med, Sao Paulo, Brazil

[34] Mayo Clin, Coll Med, Dept Hlth Sci Res, Div Rheumatol, Rochester, MN USA

来源：

ARTHRITIS & RHEUMATOLOGY | 2015年 / 67卷 / 10期

基金：

美国国家卫生研究院;

关键词：

ERYTHROCYTE SEDIMENTATION-RATE; GIANT-CELL ARTERITIS; PROVISIONAL CLASSIFICATION CRITERIA; DOSE GLUCOCORTICOID THERAPY; EULAR RECOMMENDATIONS; FOLLOW-UP; DOUBLE-BLIND; MUSCULOSKELETAL MANIFESTATIONS; CLINICAL CHARACTERISTICS; DIURNAL-VARIATION;

D O I：

10.1002/art.39333

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Therapy for polymyalgia rheumatica (PMR) varies widely in clinical practice as international recommendations for PMR treatment are not currently available. In this paper, we report the 2015 European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) recommendations for the management of PMR. We used the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) methodology as a framework for the project. Accordingly, the direction and strength of the recommendations are based on the quality of evidence, the balance between desirable and undesirable effects, patients' and clinicians' values and preferences, and resource use. Eight overarching principles and nine specific recommendations were developed covering several aspects of PMR, including basic and follow-up investigations of patients under treatment, risk factor assessment, medical access for patients and specialist referral, treatment strategies such as initial glucocorticoid (GC) doses and subsequent tapering regimens, use of intramuscular GCs and disease modifying anti-rheumatic drugs (DMARDs), as well as the roles of non-steroidal anti-rheumatic drugs and non-pharmacological interventions. These recommendations will inform primary, secondary and tertiary care physicians about an international consensus on the management of PMR. These recommendations should serve to inform clinicians about best practices in the care of patients with PMR.

引用

页码：2569 / 2580

页数：12

共 78 条

[11] Polymyalgia rheumatica in primary care: a cohort study of the diagnostic criteria and outcome [J].