ICEHpsaHPS7, a Novel Multiple Drug Resistance Integrative Conjugative Element in Glaesserella parasuis

被引：10
作者：
An, Jiahui [1 ,2 ]
Guo, Genglin [1 ,2 ,3 ]
Yu, Dong [1 ,2 ]
Zhu, Kexin [1 ,2 ]
Zhang, Chao [1 ,2 ]
Li, Yufeng [1 ,2 ]
机构：
[1] Minist Agr, Key Lab Bacteriol, Nanjing, Peoples R China
[2] Nanjing Agr Univ, Coll Vet Med, Nanjing, Peoples R China
[3] OIE Reference Lab Swine Streptococcosis, Nanjing, Peoples R China
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2021年 / 65卷 / 02期
关键词：
transconjugant; Glaesserella (Haemophilus) parasuis; integrative conjugative element; multidrug resistance; transconjugation; HAEMOPHILUS-PARASUIS; ANTIMICROBIAL SUSCEPTIBILITY; IV SECRETION; PIGS; ICE;
D O I：
10.1128/AAC.01716-20
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Integrative conjugative elements (ICEs) are a kind of novel self-transmissible mobile genetic element. In this study, a novel ICE was identified in Glaesserella (Haemophilus) parasuis. We confirmed that it could mediate the migration of antimicrobial resistance genes in G. parasuis and found that there may have been a transferring potential between different serovar strains of G. parasuis. These findings demonstrate that the ICE is crucial to the horizontal transfer of antimicrobial resistance among G. parasuis strains.
引用
收藏
页数：8
相关论文
共 25 条
[1]   Antimicrobial susceptibility of Haemophilus parasuis and Histophilus somni from pigs and cattle in Denmark [J].
Aarestrup, FM ;
Seyfarth, AM ;
Angen, O .
VETERINARY MICROBIOLOGY, 2004, 101 (02) :143-146
[2]   Shaping bacterial genomes with integrative and conjugative elements [J].
Burrus, V ;
Waldor, MK .
RESEARCH IN MICROBIOLOGY, 2004, 155 (05) :376-386
[3]   Conjugative transposons:: the tip of the iceberg [J].
Burrus, V ;
Pavlovic, G ;
Decaris, B ;
Guédon, G .
MOLECULAR MICROBIOLOGY, 2002, 46 (03) :601-610
[4]   BLAST plus : architecture and applications [J].
Camacho, Christiam ;
Coulouris, George ;
Avagyan, Vahram ;
Ma, Ning ;
Papadopoulos, Jason ;
Bealer, Kevin ;
Madden, Thomas L. .
BMC BIOINFORMATICS, 2009, 10
[5]   Type IV secretion:: the Agrobacterium VirB/D4 and related conjugation systems [J].
Christie, PJ .
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2004, 1694 (1-3) :219-234
[6]   Biogenesis, architecture, and function of bacterial type IV secretion systems [J].
Christie, PJ ;
Atmakuri, K ;
Krishnamoorthy, V ;
Jakubowski, S ;
Cascales, E .
ANNUAL REVIEW OF MICROBIOLOGY, 2005, 59 :451-485
[7]   Update on Glasser's disease: How to control the disease under restrictive use of antimicrobials [J].
Costa-Hurtado, Mar ;
Barba-Vidal, Emili ;
Maldonado, Jaime ;
Aragon, Virginia .
VETERINARY MICROBIOLOGY, 2020, 242
[8]   Why and how antibiotics are used in swine production [J].
Cromwell, GL .
ANIMAL BIOTECHNOLOGY, 2002, 13 (01) :7-27
[9]   Integrating conjugative elements of the SXT/R391 family trigger the excision and drive the mobilization of a new class of Vibrio genomic islands [J].
Daccord, Aurelie ;
Ceccarelli, Daniela ;
Burrus, Vincent .
MOLECULAR MICROBIOLOGY, 2010, 78 (03) :576-588
[10]   progressiveMauve: Multiple Genome Alignment with Gene Gain, Loss and Rearrangement [J].
Darling, Aaron E. ;
Mau, Bob ;
Perna, Nicole T. .
PLOS ONE, 2010, 5 (06)
123