DNA REPAIR A unifying mechanism in neurodegeneration

被引:44
|
作者
Ross, Christopher A. [1 ,2 ,3 ,4 ]
Truant, Ray [5 ]
机构
[1] Johns Hopkins Univ, Sch Med, Dept Psychiat, Baltimore, MD 21287 USA
[2] Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21287 USA
[3] Johns Hopkins Univ, Sch Med, Dept Neurosci, Baltimore, MD 21287 USA
[4] Johns Hopkins Univ, Sch Med, Dept Pharmacol, Baltimore, MD 21287 USA
[5] McMaster Univ, Dept Biochem & Biomed Sci, Hamilton, ON L8N 3Z5, Canada
关键词
OXIDATION;
D O I
10.1038/nature21107
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Identification of a previously uncharacterized genetic disease highlights DNA repair as a shared mechanism in neurodegenerative disorders, and suggests potential therapeutic approaches to tackling them. See Letter p.87
引用
收藏
页码:34 / 35
页数:3
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